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: Diabetic Nephropathy

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Gabriella Gruden and the scientists and students working in her Lab are devoted to the study of the cellular and molecular mechanisms implicated in the both the onset and the progression of diabetic nephropathy. Our goal is to identify new targets for therapeutic intervention and discover novel biomarkers for early diagnosis and prognosis. We work in vitro on glomerular cells exposed to diabetes-related insults, in vivo in animal models of diabetes, ex-vivo on human renal biopsies and biological samples (blood, urine). 

 

We are currently engaged in active basic research programs focusing on the role of the endocannabinoid system, miRNA, inflammation, and cell to cell communication (exosomes, nanotubes) in the pathogenesis of diabetic nephropathy. Furthermore, we are actively involved in early biomarker discovery in metabolic and diabetic complications as members of the EURODIAB, the EURODIAB PCS, and the RIACE Study Group.

 

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          Endocannabinoids                            miRNA                                    Exosome TNT                              Inflammation                          EUROBIAB Study                                   

       Relevant publications                                  Relevant publications                          Relevant publications                            Relevant publications                         Relevant publications                                
 

  

       upload_pio1.jpg Dr. Federica Barutta post-doc 

        Federica Barutta has been awarded a European Federation for the Study of Diabetes (EFSD) Research Fellowship in Diabetes

        Microvascular Complications in 2011 and she is currently the recipient of a three-years Post-Doctoral JDRF Fellowship.

  

 

 

upload_sere1.jpg       Dr. Serena Grimaldi PhD. Student

       Serena Grimaldi is a PhD. student and she is currently working on a research project on

       the role of miRNA in diabetic nephropathy, funded by the EFSD.

 

 

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         Prof. Gabriella Gruden Group Leader

        Gabriella Gruden has a degree in Medicine, a Specialisation in Internal Medicine, and a PhD degree (University of London)

        She has been working for over twenty years in the field of diabetic nephropathy both in Italy and the UK. 

 

 

 

RELEVANT WEBSITES:

Società Italiana di Diabetologica: http://www.siditalia.it/

European Diabetic Nephropathy Study Group: http://www.ednsg.org/

European Association for the Study of Diabetes: http://www.easd.org/

American Diabetes Association: http://professional.diabetes.org/?loc=bb-dorg

International Diabetes Federation: http://www.idf.org

European Foundation for Study of Diabetes:  http://www.europeandiabetesfoundation.org

JDRF: http://jdrf.org/

Publications

Penno G, Solini A, Zoppini G, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Gruden G, Lamacchia O, Laviola L, Orsi E, Pugliese G; Renal Insufficiency Cardiovascular Events (RIACE) Study Group. Independent correlates of urinary albumin excretion within the normoalbuminuric range in patients with type 2 diabetes: The Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study. Acta Diabetol. 2015 Jul 10.

Bo S, Gruden G, Charbonnier E, Martorana M, Gambino R, Cassader M, Gentile L, Cavallo-Perin P, Durazzo M (2014)
High-normal blood pressure and impaired renal function. A prospective study in a population-based cohort.
https://iris.unito.it/handle/2318/148416

Gruden G, Landi A, Bruno G (2014)
Natriuretic peptides, heart, and adipose tissue: new findings and future developments for diabetes research.
https://iris.unito.it/handle/2318/154815

Pugliese G, Solini A, Bonora E, Orsi E, Zerbini G, Fondelli C, Gruden G, Cavalot F, Lamacchia O, Trevisan R, Vedovato M, Penno G (2014)
Distribution of cardiovascular disease and retinopathy in patients with type 2 diabetes according to different classification systems for chronic kidney disease: a cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study.
https://iris.unito.it/handle/2318/154817

Barutta F, Grimaldi S, Franco I, Bellini S, Gambino R, Pinach S, Corbelli A, Bruno G, Rastaldi MP, Aveta T, Hirsch E, Di Marzo V, Gruden G (2014)
Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice.
https://iris.unito.it/handle/2318/154816

Bruno G, Barutta F, Landi A, Cavallo Perin P, Gruden G (2014)
The Effect of Age and NT-proBNP on the Association of Central Obesity with 6-Years Cardiovascular Mortality of Middle-Aged and Elderly Diabetic People: The Population-Based Casale Monferrato Study.
https://iris.unito.it/handle/2318/148222

Graziella Bruno, Federica Barutta, Andrea Landi, Paolo Cavallo Perin, Gabriella Gruden (2014)
NT-proBNP Linking Low-Moderately Impaired Renal Function and Cardiovascular Mortality in Diabetic Patients: The Population-Based Casale Monferrato Study.
https://iris.unito.it/handle/2318/154840

Lorenzati B, Ianni Palrchio A, Barutta F, Gruden G (2013)
Mechanical stretch and angiotensin II activate Janus tyrosine kinase-2 in human podocytes.
https://iris.unito.it/handle/2318/136124

Barutta F, Tricarico F, Corbelli A, Annaratone L, Pinach S, Grimaldi S, Bruno G, Cimino D, Taverna D, Deregibus MC, Rastaldi MP, Cavallo Perin P, Gruden G (2013)
Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy.
https://iris.unito.it/handle/2318/139842

Lorenzati B, Barale M, Amione C, Tricarico M, Gruden G (2013)
Adult corkscrew ureter.
https://iris.unito.it/handle/2318/147760

Massa F, Tarabra E, Barutta F, Pinach S, Gruden G (2013)
Mechanical stretch induces fibronectin production in human podocytes via a TGF-beta 1-dependent mechanism.
https://iris.unito.it/handle/2318/139125

Pinach S, Burt D, Berrone E, Barutta F, Bruno G, Porta M, Perin PC, Gruden G (2013)
Retinal heat shock protein 25 in early experimental diabetes.
https://iris.unito.it/handle/2318/130058

Bruno G, Spadea T, Picariello R, Gruden G, Barutta F, Cerutti F, Cavallo-Perin p, Costa G, Gnavi R, Piedmont Study Group for Diabetes Epidemiology (2013)
Early life socioeconomic indicators and the risk of type 1 diabetes in children and young adults.
https://iris.unito.it/handle/2318/129939

M Trento, F Panero, M Porta, G Gruden, F Barutta, F Cerutti, R Gambino, M Perotto, P Cavallo Perin, G Bruno (2013)
Diabetes-specific variables associated with quality of life changes in young diabetic people: the type 1 diabetes Registry of Turin (Italy).
https://iris.unito.it/handle/2318/127978

Penno G, Solini A, Bonora E, Fondelli C, Orsi E, Zerbini G, Trevisan R, Vedovato M, Gruden G, Laviola L, Nicolucci A, Pugliese G, The Renal Insufficiency Cardiovascular Events (RIACE) study group (2013)
Gender differences in cardiovascular disease risk factors, treatments and complications in patients with type 2 diabetes: the RIACE Italian multicentre study.
https://iris.unito.it/handle/2318/128370

Panero F, Gruden G, Zucco C, Prinzis T, Perotto M, Greco E, Bruno G (2013)
Delayed discharge: a rising cause of concern in general internal medicine wards.
https://iris.unito.it/handle/2318/127534

Villois P, Tricarico M, Gruden G, Cavallo Perin P (2013)
Silicone lymphadenopathy after silent Silicone breast implant rupture.
https://iris.unito.it/handle/2318/139126

Pagano E, Gray A, Rosato R, Gruden G, Cavallo Perin P, Merletti F, Bruno G (2013)
Prediction of mortality and macrovascular complications in type 2 diabetes: validation of the UKPDS Outcomes Model in the Casale Monferrato survey, Italy.
https://iris.unito.it/handle/2318/128303

Gruden G, Barutta F, Pinach S, Lorenzati B, Cavallo-Perin P, Giunti S, Bruno G (2013)
Circulating anti-Hsp70 levels in nascent metabolic syndrome: the Casale Monferrato Study.
https://iris.unito.it/handle/2318/129683

Gruden G, Carucci P, Lolli V, Cosso L, Dellavalle E, Rolle E, Cantamessa A, Pinach S, Abate ML, Campra D, Brunello F, Bruno G, Rizzetto M, Perin PC (2013)
Serum heat shock protein 27 levels in patients with hepatocellular carcinoma.
https://iris.unito.it/handle/2318/120330

Bruno G, Landi A, Barutta F, Ghezzo G, Baldin C, Spadafora L, Schimmenti A, Prinzis T, Cavallo Perin P, Gruden G (2013)
NH2-Terminal Probrain Natriuretic Peptide Is a Stronger Predictor of Cardiovascular Mortality Than C-Reactive Protein and Albumin Excretion Rate in Elderly Patients With Type 2 Diabetes: The Casale Monferrato population-based study.
https://iris.unito.it/handle/2318/127110

Gruden G, Barutta F, Catto I, Bosco G, Caprioli MG, Pinach S, Fornengo P, Cavallo-Perin P, Davini O, Cerrato P, Bruno G (2013)
Serum levels of heat shock protein 27 in patients with acute ischemic stroke.
https://iris.unito.it/handle/2318/129629

Lombardo F, Maggini M, Gruden G, Bruno G (2013)
Temporal trend in hospitalizations for acute diabetic complications: a nationwide study, Italy, 2001-2010.
https://iris.unito.it/handle/2318/135728

Mannucci M, Nobili A, Tettamanti M, Pasina L, Franchi C, Salerno F, Corrao S, Marengoni A, Iorio A, Marcucci M, Sparacio E, Alborghetti S, Di Costanzo R, Tettamanti M, Djade CD, Prisco D, Silvestri E, Cenci C, Barnini T, Delitala G, Carta S, Atzori S, Guarnieri G, Zanetti M, Spalluti A, Serra MG, Bleve MA, Di Corato P, Vanoli M, Grignani G, Casella G, Gasbarrone L, Maniscalco G, Gunelli M, Tirotta D, Brucato A, Ghidoni S, Bernardi M, Li Bassi S, Santi L, Agnelli G, Iorio A, Marcucci M, Marchesini E, Mannarino E, Lupattelli G, Rondelli P, Paciullo F, Fabris F, Carlon M, Turatto F, Baroni MC, Zardo M, Manfredini R, Molino C, Pala M, Fabbian F, Nuti R, Valenti R, Ruvio M, Cappelli S, Paolisso G, Rizzo MR, Laieta MT, Salvatore T, Sasso FC, Utili R, Durante Mangoni E, Pinto D, Olivieri O, Stanzial AM, Fellin R, Volpato S, Fotini S, Barbagallo M, Dominguez L, Plances L, DAngelo D, Rini G, Mansueto P, Pepe I, Licata G, Calvo L, Valenti M, Borghi C, Strocchi E, Rinaldi ER, Zoli M, Fabbri E, Magalotti D, Auteri A, Pasqui AL, Puccetti L, Pasini FL, Capecchi PL, Bicchi M, Sabbà C, Vella FS, Marseglia A, Luglio CV, Palasciano G, Modeo ME, Aquilino A, Raffaele P, Pugliese S, Capobianco C, Postiglione A, Barbella MR, De Stefano F, Fenoglio L, Brignone C, Bracco C, Giraudo A, Musca G, Cuccurullo O, Cricco L, Fiorentini A, Cappellini MD, Fabio G, Seghezzi S, De Amicis MM, Fargion S, Bonara P, Bulgheroni M, Lombardi R, Magrini F, Massari F, Tonella T, Peyvandi F, Tedeschi A, Rossio R, Moreo G, Ferrari B, Roncari L, Monzani V, Savojardo V, Folli C, Magnini M, Mari D, Rossi PD, Damanti S, Prolo S, Lilleri MS, Cricco L, Fiorentini A, Micale G, Podda M, Selmi C, Meda F, Salerno F, Accordino S, Conca A, Monti V, Corazza GR, Miceli E, Lenti MV, Padula D, Balduini CL, Bertolino G, Provini S, Quaglia F, Murialdo G, Bovio M, Dallegri F, Ottonello L, Quercioli A, Barreca A, Secchi MB, Ghelfi D, Chin WS, Carassale L, Caporotundo S, Sofia L, Anastasio L, Carbone M, Di Carlo S, Traisci G, De Feudis L, Davì G, Guagnano MT, Sestili S, Bergami E, Rizzioli E, Cagnoni C, Bertone L, Manucra A, Buratti A, Tognin T, Liberato NL, Bernasconi G, Nardo B, Bianchi GB, Benetti G, Quagliolo M, Centenaro GR, Purrello F, Di Pino A, Piro S, Mancuso G, Calipari D, Bartone M, Gullo F, Cortellaro M, Magenta M, Perego F, Meroni MR, Cicardi M, Magenta AG, Sacco A, Bonelli A, Dentamaro G, Rozzini R, Falanga L, Giordano A, Perin PC, Lorenzati B, Gruden G, Bruno G, Montrucchio G, Greco E, Tizzani P, Fera G, Di Luca ML, Renna D, Perciccante A, Coralli A, Tassara R, Melis D, Rebella L, Menardo G, Bottone S, Sferrazzo E, Ferri C, Striuli R, Scipioni R, Salmi R, Gaudenzi P, Gamberini S, Ricci F, Morabito C, Fava R, Semplicini A, Gottardo L, Delitala G, Carta S, Atzori S, Vendemiale G, Serviddio G, Forlano R, Bolondi L, Rasciti L, Serio I, Masala C, Mammarella A, Raparelli V, Rossi Fanelli F, Delfino M, Amoroso A, Violi F, Basili S, Perri L, Serra P, Fontana V, Falcone M, Landolfi R, Grieco A, Gallo A, Zuccalà G, Franceschi F, De Marco G, Chiara C, Marta S, Bellusci M, Setti D, Pedrazzoli F, Romanelli G, Pirali C, Amolini C, Rosei EA, Rizzoni D, Castoldi L, Picardi A, Gentilucci UV, Mazzarelli C, Gallo P, Guasti L, Castiglioni L, Maresca A, Squizzato A, Contini S, Molaro M, Annoni G, Zazzetta MC, Bertolotti M, Scotto CM, Ferri MA, Veltri F, Arturi F, Succurro E, Sesti G, Gualtieri U, Perticone F, Sciacqua A, Quero M, Bagnato C, Loria P, Becchi MA, Martucci G, Fantuzzi A, Maurantonio M, Corinaldesi R, De Giorgio R, Serra M, Grasso V, Ruggeri E, Carozza LM, Pignatti F (2013)
Prophylaxis of venous thromboembolism in elderly patients with multimorbidity.
https://iris.unito.it/handle/2318/149223

Perotto M, Panero F, Gruden G, Fornengo P, Lorenzati B, Barutta F, Ghezzo G, Amione C, Cavallo Perin P, Bruno G (2013)
Obesity is associated with lower mortality risk in elderly diabetic subjects: the Casale Monferrato study.
https://iris.unito.it/handle/2318/129998

Marcucci M, Nobili A, Tettamanti M, Iorio A, Pasina L, Djade CD, Franchi C, Marengoni A, Salerno F, Corrao S, Violi F, Mannucci PM, Pier MM, Nobili A, Tettamanti M, Pasina L, Franchi C, Salerno F, Corrao S, Marengoni A, Iorio A, Marcucci M, Spirito V, Noce D, Bonazzi J, Lombardo R, Sparacio E, Alborghetti S, Tettamanti M, De Vittorio L, Djade CD, Prisco D, Silvestri E, Cenci C, Barnini T, Delitala G, Carta S, Atzori S, Guarnieri G, Zanetti M, Spalluti A, Serra MG, Bleve MA, Vanoli M, Grignani G, Casella G, Gasbarrone L, Maniscalco G, Gunelli M, Tirotta D, Brucato A, Ghidoni S, Di Corato P, Bernardi M, Li Bassi S, Santi L, Agnelli G, Iorio A, Marcucci M, Marchesini E, Mannarino E, Lupattelli G, Rondelli P, Paciullo F, Fabris F, Carlon M, Turatto F, Baroni MC, Zardo M, Manfredini R, Molino C, Pala M, Fabbian F, Nuti R, Valenti R, Ruvio M, Cappelli S, Paolisso G, Rizzo MR, Laieta MT, Salvatore T, Sasso FC, Utili R, Durante Mangoni E, Pinto D, Olivieri O, Stanzial AM, Fellin R, Volpato S, Fotini S, Barbagallo M, Dominguez L, Plances L, D', Angelo D, Rini G, Mansueto P, Pepe I, Licata G, Calvo L, Valenti M, Borghi C, Strocchi E, Rinaldi ER, Zoli M, Fabbri E, Magalotti D, Auteri A, Pasqui AL, Puccetti L, Pasini FL, Capecchi PL, Bicchi M, Sabbà C, Vella FS, Marseglia A, Luglio CV, Palasciano G, Modeo ME, Aquilino A, Raffaele P, Pugliese S, Capobianco C, Postiglione A, Barbella MR, De Stefano F, Fenoglio L, Brignone C, Bracco C, Giraudo A, Musca G, Cuccurullo O, Cricco L, Fiorentini A, Cappellini MD, Fabio G, Seghezzi S, De Amicis MM, Fargion S, Bonara P, Bulgheroni M, Lombardi R, Magrini F, Massari F, Tonella T, Peyvandi F, Tedeschi A, Rossio R, Moreo G, Ferrari B, Roncari L, Monzani V, Savojardo V, Folli C, Magnini M, Mari D, Dionigi Rossi P, Damanti S, Prolo S, Lilleri MS, Cricco L, Fiorentini A, Micale G, Podda M, Selmi C, Meda F, Salerno F, Accordino S, Conca A, Monti V, Corazza GR, Miceli E, Lenti MV, Padula D, Balduini CL, Bertolino G, Provini S, Quaglia F, Murialdo G, Bovio M, Dallegri F, Ottonello L, Quercioli A, Barreca A, Secchi MB, Ghelfi D, Chin WS, Carassale L, Caporotundo S, Sofia L, Anastasio L, Carbone M, Traisci G, De Feudis L, Di Carlo S, Guagnano MT, Sestili S, Bergami E, Rizzioli E, Cagnoni C, Bertone L, Manucra A, Buratti A, Tognin T, Liberato NL, Bernasconi G, Nardo B, Bianchi GB, Giaquinto S, Benetti G, Quagliolo M, Centenaro GR, Purrello F, Di Pino A, Piro S, Mancuso G, Calipari D, Bartone M, Gullo F, Cortellaro M, Magenta M, Perego F, Meroni MR, Cicardi M, Magenta AG, Sacco A, Bonelli A, Dentamaro G, Rozzini R, Falanga L, Giordano A, Perin PC, Lorenzati B, Gruden G, Bruno G, Montrucchio G, Greco E, Tizzani P, Fera G, Di Luca ML, Renna D, Perciccante A, Coralli A, Tassara R, Melis D, Rebella L, Menardo G, Bottone S, Sferrazzo E, Ferri C, Striuli R, Scipioni R, Salmi R, Gaudenzi P, Gamberini S, Ricci F, Morabito C, Fava R, Semplicini A, Gottardo L, Delitala G, Carta S, Atzori S, Vendemiale G, Serviddio G, Forlano R, Bolondi L, Rasciti L, Serio I, Masala C, Mammarella A, Raparelli V, Rossi Fanelli F, Delfino M, Amoroso A, Violi F, Basili S, Perri L, Serra P, Fontana V, Falcone M, Landolfi R, Grieco A, Gallo A, Zuccalà G, Franceschi F, De Marco G, Chiara C, Marta S, Bellusci M, Setti D, Pedrazzoli F, Romanelli G, Pirali C, Amolini C, Rosei EA, Rizzoni D, Castoldi L, Picardi A, Gentilucci UV, Mazzarelli C, Gallo P, Guasti L, Castiglioni L, Maresca A, Squizzato A, Contini S, Molaro M, Annoni G, Zazzetta MC, Bertolotti M, Scotto CM, Ferri MA, Veltri F, Arturi F, Succurro E, Sesti G, Gualtieri U, Perticone F, Sciacqua A, Quero M, Bagnato C, Loria P, Becchi MA, Martucci G, Fantuzzi A, Maurantonio M, Corinaldesi R, De Giorgio R, Serra M, Grasso V, Ruggeri E, Carozza LM, Pignatti F (2013)
Joint use of cardio-embolic and bleeding risk scorers in elderly patients with atrial fibrillation.
https://iris.unito.it/handle/2318/149221

Pugliese G, Solini A, Zoppini G, Orsi E, Zerbini G, Vedovato M, Gruden G, Cavalot F, Cignarelli M, Morano S, Nicolucci A, Penno G (2012)
Attuale prevalenza e correlate della retinopatia in pazienti con diabete di tipo 2: lo studio RIACE.
https://iris.unito.it/handle/2318/118874

Lorenzati B, Giunti S, Barutta F, Pinach S, Amione C, Tricarico M, Landi A, Schimmenti A, Cavallo Perin P, Bruno G, Gruden G (2012)
Associazione tra anti-HSP70 e sindrome plurimetabolica: il Casale Monferrato Study.
https://iris.unito.it/handle/2318/119422

Barutta F, Tricarico M, Corbelli A, Pinach S, Grimaldi S, Bruno G, Rastaldi M, Cavallo Perin P, Gruden G (2012)
Urinary exosomal microRNA signature in incipient diabetic nephropathy.
https://iris.unito.it/handle/2318/117435

Landi A, Gruden G, Ghezzo G, Baldin C, Amione C, Schimmenti A, Spadafora L, Trinzis T, Cavallo Perin P, Bruno G (2012)
N-terminal pro-brain natriuretic peptide and cardiovascular mortality in type 2 diabetes: the Casale Monferrato survey.
https://iris.unito.it/handle/2318/118656

Panero F, Gruden G, Perotto M, Fornengo P, Barutta F, Greco E, Runzo C, Ghezzo G, Cavallo-Perin P, Bruno G (2012)
Uric acid is not an independent predictor of cardiovascular mortality in type 2 diabetes: a population-based study.
https://iris.unito.it/handle/2318/129238

Mastrocola R, Barutta F, Pinach S, Bruno G, Perin PC, Gruden G (2012)
Hippocampal heat shock protein 25 expression in streptozotocin-induced diabetic mice.
https://iris.unito.it/handle/2318/133327

Lorenzati B, Giunti S, Barutta F, PInach S, Cavallo Perin P, Bruno G, Gruden G (2012)
Anti-HSP70 levels and the metabolic syndrome: the Casale Monferrato Study.
https://iris.unito.it/handle/2318/117218

Penno G, Solini A, Zoppini G, Orsi E, Zerbini G, Trevisan R, Gruden G, Cavalot F, Laviola L, Morano S, Nicolucci A, Pugliese G (2012)
Rate and Determinants of Association Between Advanced Retinopathy and Chronic Kidney Disease in Patients With Type 2 Diabetes: The Renal Insufficiency And Cardiovascular Events (RIACE) Italian multicenter study.
https://iris.unito.it/handle/2318/120759

Trevisan M, Rabullo M, Trinetta A, Gallo S, Gruden G, Tonutti L, Passera P, Boggio Bertinet D, Charrier L, Cavallo F, Porta M, Trento M (2012)
Verifica dei disturbi del comportamento alimentare, qualità di vita, ansia e depressione nelle donne con diabete di tipo 1.
https://iris.unito.it/handle/2318/119571

Gruden G, Barutta F, Chaturvedi N, Schalkwijk C, Stehouwer CD, Witte DR, Fuller JH, Cavallo Perin P, Bruno G (2012)
Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes: The EURODIAB Prospective Complications Study.
https://iris.unito.it/handle/2318/106986

Gruden G, Barutta F, Chaturvedi N, Schalkwijk C, Stehouwer CD, Pinach S, Manzo M, Loiacono M, Tricarico M, Mengozzi G, Witte DR, Fuller JH, Perin PC, Bruno G (2012)
NH2-Terminal Probrain Natriuretic Peptide Is Associated With Diabetes Complications in the EURODIAB Prospective Complications Study: The role of tumor necrosis factor-?
https://iris.unito.it/handle/2318/107085

Gruden G, Barutta F, Cavallo Perin P, Bruno G (2012)
Response to Comment on: Gruden et al. Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes: The EURODIAB Prospective Complications Study. Diabetes Care 2012;35:1598-1604.
https://iris.unito.it/handle/2318/127585

Gruden G, Giunti S, Barutta F, Chaturvedi N, Witte DR, Tricarico M, Fuller JH, Cavallo Perin P, Bruno G (2012)
QTc Interval Prolongation Is Independently Associated With Severe Hypoglycemic Attacks in Type 1 Diabetes From the EURODIAB IDDM Complications Study.
https://iris.unito.it/handle/2318/92842

Giunti S, Gruden G, Fornengo P, Barutta F, Amione C, Grezzo G, Cavallo-Perin P, Bruno G (2012)
Increased QT interval dispersion predicts 15-years cardiovascular mortality in type 2 diabetic subjects. The population-based Casale Monferrato Study.
https://iris.unito.it/handle/2318/131798

Pugliese G, Penno G, Bonora E, Orsi E, Zerbini G, Fondelli C, Gruden G, Cavalot F, Cignarelli M, Laviola L, Morano S, Vedovato M, Trevisan R, Nicolocci A, Solini A (2011)
Association of normoalbuminuric renal impairment with cardiovascular disease.
https://iris.unito.it/handle/2318/92475

Gruden G (2011)
I farmaci inibitori del sistema RAS.
https://iris.unito.it/handle/2318/92257

Barutta F, Corbelli A, Pinach S, Rastaldi MP, Cavallo Perin P, Gruden G (2011)
Effect of CB2 receptor deletion in streptozotocin-induced diabetic mice.
https://iris.unito.it/handle/2318/92159

Barutta F, Piscitelli F, Pinach S, Bruno G, Gambino R, Rastaldi MP, Salvidio G, Di Marzo V, Cavallo Perin P, Gruden G (2011)
Protective role of cannabinoid receptor type-2 in a mouse model of diabetic nephropathy.
https://iris.unito.it/handle/2318/127751

Penno G, Solini A, Bonora E, Fondelli C, Orsi E, Zerbini G, Trevisan R, Vedovato M, Gruden G, Cavalot F, Cignarelli M, Laviola L, Morano S, Nicolucci A, Pugliese G (2011)
Clinical significance of nonalbuminuric renal impairment in type 2 diabetes.
https://iris.unito.it/handle/2318/92762

Gruden G (2010)
Nefropatia Diabetica.
https://iris.unito.it/handle/2318/77726

Pugliese, Solini A, Bonora E, Orsi E, Zerbini G, Fondelli C, Morano S, Cignarelli M, Laviola L, Cavalot FL, Gruden G, Trevisan R, Vedovato M, Nicolucci A, Penno A (2010)
Cardiovascular risk factors and micro- and macrovascular complications in patients with type 2 diabetes in Italy.
https://iris.unito.it/handle/2318/119064

Barutta F, Gambino R, Pinach S, Cavallo Perin P, Gruden G (2010)
Effect of CB2 Receptor Activation in Experimental Diabetic Nephropathy.
https://iris.unito.it/handle/2318/82340

Gruden G (2010)
Ipertensione arteriosa.
https://iris.unito.it/handle/2318/77725

Bruno G, De Micheli A, Frontoni S, Monge L, Bonomo M, De Cosmo S, Grassi G, Nicolucci A, Aiello A, Bertuzzi F, Bonora E, Cimino A, Cordera R, de Bigontina G, Di Bartolo P, Dotta F, Frittitta L, Giaccari A, Giorgino F, Gruden G, Marchetti P, Meschi F, Pellegrini MA, Rivellese A, Sesti G (2010)
Highlights from ?Italian Standards of Care for Diabetes Mellitus 2009?2010?
https://iris.unito.it/handle/2318/133503

Setti G, Hayward A, Dessapt C, Barone F, Buckingham R, White K, Bilous R, Hiroshi K, Gruden G, Viberti G, Gnudi L (2010)
Peroxisome proliferator-activated receptor-? agonist rosiglitazone prevents albuminuria but not glomerulosclerosis in experimental diabetes.
https://iris.unito.it/handle/2318/79299

Gruden G, Giunti S (2010)
Diabete mellito e ipoglicemie.
https://iris.unito.it/handle/2318/79930

Barutta F, Gambino R, Pinach S, Cavallo Perin P, Gruden G (2010)
ATTIVAZIONE DEL RECETTORE CB2 E NEFROPATIA DIABETICA SPERIMENTALE.
https://iris.unito.it/handle/2318/81498

Giunti S, Barutta F, Perin PC, Gruden G (2010)
Targeting the MCP-1/CCR2 System in diabetic kidney disease.
https://iris.unito.it/handle/2318/82892

Miceli I, Burt D, Tarabra E, Camussi G, Perin PC, Gruden G (2010)
Stretch reduces nephrin expression via an angiotensin II-AT(1)-dependent mechanism in human podocytes: effect of rosiglitazone.
https://iris.unito.it/handle/2318/82025

Barutta F, Gambino R, Cavallo Perin P, Gruden G (2010)
Ruolo protettivo del recettore CB2 nella nefropatia diabetica sperimentale.
https://iris.unito.it/handle/2318/82338

Barutta F, Corbelli A, Mastrocola R, Gambino R, Di Marzo V, Pinach S, Rastaldi MP, Perin PC, Gruden G (2010)
Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy.
https://iris.unito.it/handle/2318/79300

Tarabra E, Giunti S, Barutta F, Salvidio G, Burt D, Deferrari G, Gambino R, Vergola D, Pinach S, Cavallo Perin P, Camussi G, Gruden G (2009)
Effect of the MCP-1/CCR2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes.
https://iris.unito.it/handle/2318/66339

Lorenzati B, Gruden G (2009)
Ipertensione arteriosa e microangiopatia: un rapporto complesso.
https://iris.unito.it/handle/2318/129562

Barutta F, Giunti S, Mastrocola R, Pinach S, Giardino L, Rastaldi MP, Cavallo Perin P, Gruden G (2009)
Effects of CB1 Blockade In Experimental Diabetic Nephropathy.
https://iris.unito.it/handle/2318/75917

Cosso L, Carucci P, Gruden G, Lolli V, Rolle E, Pinach S, Abate ML, Brunello F, Bruno G, Rizzetto M, Cavallo Perin P (2009)
Serum heat shock protein 27 is a new circulating biomarker for hepatocellular carcinoma.
https://iris.unito.it/handle/2318/120284

Barutta F, Giunti S, Mastrocola R, Pinach S, Giardino L, Rastaldi MP, Cavallo Perin P, Gruden G (2009)
Il blocco del recettore CB1 nella nefropatia diabetica sperimentale.
https://iris.unito.it/handle/2318/87393

Burt D, Bruno G, Chaturvedi N, Schalkwijk C, Stehouwer CD, Witte DR, Fuller JH, Pinach S, Perin PC, Gruden G (2009)
Anti-heat shock protein 27 antibody levels and diabetes complications in the EURODIAB study.
https://iris.unito.it/handle/2318/130355

Gruden G, Bruno G, Chaturvedi N, Burt D, Pinach S, Schalkwijk C, Stehouwer CD, Witte DR, Fuller JH, Cavallo Perin P (2009)
ANTI-HSP60 and ANTI-HSP70 antibody levels and micro/ macrovascular complications in type 1 diabetes: the EURODIAB Study.
https://iris.unito.it/handle/2318/126845

Barutta F, Giunti S, Mastrocola R, Pinach S, Giardino L, , , Rastaldi MP, Cavallo Perin P, Gruden G (2009)
Il blocco del recettore CB1 nella nefropatia diabetica sperimentale.
https://iris.unito.it/handle/2318/76161

Rispoli P, Casella F, Lorenzati B, Guerzoni V, Gruden G, Conforti M, Varetto G (2009)
Isolated dissection of the superior mesenteric artery: conservative approach in a selected patient.
https://iris.unito.it/handle/2318/79955

Burt D, Pinach S, Berrone E, Miceli I, Porta M, Cavallo Perin P, Gruden G (2008)
Increased retinal HSP27 expression in early experimental diabetes.
https://iris.unito.it/handle/2318/120701

Barutta F, Pinach S, Giunti S, Vittone F, Forbes JM, Chiarle R, Arnstein M, Perin PC, Camussi G, Cooper ME, Gruden G (2008)
Heat shock protein expression in diabetic nephropathy.
https://iris.unito.it/handle/2318/127744

Tarabra E, Massa F, Gambino R, Giunti S, Cavallo-Perin P, Camussi G, Gruden G (2008)
Espressione delle proteine dello slit DIAPHRAGM in animali diabetici knockout per il monocyte chemoattractant protein-1.
https://iris.unito.it/handle/2318/120206

GIUNTI S, TESCH GH, PINACH S, BURT DJ, COOPER ME, CAVALLO-PERIN P, CAMUSSI G, GRUDEN G (2008)
Monocyte chemoattractant protein-1 has prosclerotic effects both in a mouse model of experimental diabetes and in vitro in human mesangial cells.
https://iris.unito.it/handle/2318/25034

Pinach S, Barutta F, Forbes J, Chiarle R, Giunti S, Arnstein M, Miceli I, Cavallo Perin P, Camussi G, Cooper ME, Gruden G (2008)
Espressione delle Heat Shock Proteins nella nefropatia diabetica sperimentale.
https://iris.unito.it/handle/2318/119424

Bruno G, De Micheli A, Fedele D, Monge L, Bonomo M, Consoli A, De Cosmo S, Di Bartolo P, Di Benedetto A, Di Cianni G, Dotta F, Giaccari A, Giorgino F, Grassi G, Gruden G, Mannino D, Orlandini D, Ponziani MC, Vaccaro O, Vitacolonna E, Nicolucci A, Cimino N, de Bigontina G, Meloncelli I, Meschi M (2008)
Italian standards for diabetes mellitus 2007: executive summary.
https://iris.unito.it/handle/2318/120351

Gruden G, Bruno G, Chaturvedi N, Burt D, Schalkwijk C, Pinach S, Stehouwer CD, Witte DR, Fuller JH, Perin PC (2008)
Serum heat shock protein 27 and diabetes complications in the EURODIAB prospective complications study: a novel circulating marker for diabetic neuropathy.
https://iris.unito.it/handle/2318/99670

S GIUNTI, G BRUNO, E LILLAZ, G GRUDEN, V LOLLI, N CHATURVEDI, J H FULLER, M VEGLIO, P CAVALLO-PERIN (2007)
Incidence and risk factors of prolonged QTc interval in type 1 diabetes: the Eurodiab Prospective Complications Study.
https://iris.unito.it/handle/2318/40462

Gruden G (2007)
Ipertensione e suo trattamento.
https://iris.unito.it/handle/2318/75157

Gruden G (2007)
Screening e trattamento della nefropatia diabetica.
https://iris.unito.it/handle/2318/77700

Barutta F, Pinach S, Forbes J, Chiarle R, Giunti S, Arnstein M, Cavallo Perin P, Camussi G, Cooper ME, Gruden G (2007)
Heat shock protein expression in early diabetic nephropathy.
https://iris.unito.it/handle/2318/120702

Burt D, Bruno G, Chaturvedi N, Stehouwer CD, Pinach S, Witte D, Fuller JH, Cavallo Perin P, Gruden G (2007)
Association between serum heat shock proteins and anti-heat shock proteins levels with micro/macrovascular complications in type 1 diabetes: the EURODIAB Prospective Complications Study.
https://iris.unito.it/handle/2318/118790

Gruden G, Viberti GC (2007)
Pathogenesis of Diabetic Nephropathy.
https://iris.unito.it/handle/2318/120352

BURT D, SALVIDIO G, TARABRA E, BARUTTA F, PINACH S, DENTELLI P, CAMUSSI G, PERIN PC, GRUDEN G (2007)
The Monocyte Chemoattractant Protein-1/Cognate CC Chemokine Receptor 2 System Affects Cell Motility in Cultured Human Podocytes.
https://iris.unito.it/handle/2318/39357

E Berrone, E Beltramo, S Tarallo, S Giunti, G Gruden, P Cavallo Perin, M Porta (2006)
Effetti dello stress meccanico (stretch) combinato all?alto glucosio sulla proliferazione, l?apoptosi e la morfologia dei periciti retinici.
https://iris.unito.it/handle/2318/74825

E Beltramo, E Berrone, S Giunti, G Gruden, P Cavallo Perin, M Porta (2006)
Effects of mechanical stress and high glucose on pericyte proliferation, apoptosis and contractile phenotype.
https://iris.unito.it/handle/2318/82585

Gruppo di Studio SID Nefropatia diabetica, Pugliese G, Fioretto P, De Cosmo S, Gruden G, Morano S, Penno G, Pugliese F, Zerbini G, Gesualdo L, Solini A, Velussi M (2006)
Linee guida per lo screening, il monitoraggio, la prevenzione e il trattamento della nefropatia diabetica.
https://iris.unito.it/handle/2318/122723

S GIUNTI, S PINACH, L ARNALDI, G VIBERTI, P C PERIN, G CAMUSSI, G GRUDEN (2006)
The MCP-1/CCR2 system has direct proinflammatory effects in human mesangial cells.
https://iris.unito.it/handle/2318/39019

E Beltramo, E Berrone, S Giunti, G Gruden, P Cavallo Perin, M Porta (2005)
Effects of mechanical stress (stretch) combined with high glucose on retinal pericyte replication, apoptosis and morphology.
https://iris.unito.it/handle/2318/76840

Setti G, Gnudi L, Barone F, Hayward A, Gruden G, Buckingham R, Viberti G (2005)
Prevention of glomerular macrophages infiltration and renal MCP-1 expression by rosiglitazone in experimental diabetes.
https://iris.unito.it/handle/2318/120770

GIUNTI S, BRUNO G, VEGLIO M, GRUDEN G, WEBB D, LIVINGSTONE S, CHATURVEDI N, FULLER JH, CAVALLO-PERIN P, AND THE EURODIAB IDDM COMPLICATIONS STUDY GROUP (2005)
Electrocardiographic left ventricular hypertrophy in type 1 diabetes. Prevalence and relation to coronary heart disease and cardiovascular risk factors: The Eurodiab IDDM Complications Study.
https://iris.unito.it/handle/2318/102462

E Beltramo, E Berrone, S Giunti, G Gruden, P Cavallo Perin, M Porta (2005)
Effetti dello stress meccanico(stretch) combinato con l?alto glucosio sulla proliferazione, l?apoptosi e la morfologia dei periciti retinici.
https://iris.unito.it/handle/2318/76603

Burt D, Giunti S, Pinach S, Camussi G, Cavallo Perin P, Gruden G (2005)
Monocyte Chemoattractant Protein-1 (MCP-1) has direct prosclerotic effects in human mesangial cells.
https://iris.unito.it/handle/2318/119065

GRUDEN G, SETTI G, HAYWARD A, SUGDEN D, DUGGAN S, BURT D, BUCKINGHAM RE, GNUDI L, VIBERTI G (2005)
Mechanical stretch induces monocyte chemoattractant activity via an NF-kappaB-dependent monocyte chemoattractant protein-1-mediated pathway in human mesangial cells: inhibition by rosiglitazone.
https://iris.unito.it/handle/2318/37949

E Berrone, E Beltramo, S Tarallo, S Giunti, G Gruden, P Cavallo Perin, M Porta (2005)
Effects of mechanical stress (stretch) combined with high glucose on retinal pericyte replication, apoptosis and morphology.
https://iris.unito.it/handle/2318/77088

GRUDEN G, CAVALLO PERIN P, CAMUSSI G (2005)
Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology.
https://iris.unito.it/handle/2318/41386

Setti G, Gnudi L, Hayward A, Gruden G, Buckingham R, Viberti G (2004)
Sustained prevention of albuminuria but not nephromegaly by rosiglitazone in experimental diabetes.
https://iris.unito.it/handle/2318/118791

Giunti S, Pinach S, Palarchio AI, Arnaldi L, Vittone F, Viberti G, Camussi G, Cavallo Perin P, Gruden G (2004)
The MCP-1/CCR2 system in human mesangial cells: modulation by stretch and role in ICAM-1 expression.
https://iris.unito.it/handle/2318/119066

Gruden G, Gnudi L, Viberti GC (2004)
Pathogenesis of Diabetic Nephropathy.
https://iris.unito.it/handle/2318/37309

Setti G, Gnudi L, Hayward A, Gruden G, Buckingham R, Viberti G (2004)
Prevention of albuminuria but not nephromegaly by rosiglitazone in experimental diabetes.
https://iris.unito.it/handle/2318/118792

E Berrone, S Giunti, G Gruden, E Beltramo, C Solimine, A Ubertalli Ape, P Cavallo Perin, M Porta (2004)
Effetti dello stress meccanico (stretch) sulla proliferazione cellulare nei periciti retinici bovini in alto glucosio.
https://iris.unito.it/handle/2318/76839

Giunti S, Pinach S, Ianni Palarchio A, Arnaldi L, Vittone F, Viberti GC, Camussi G, Cavallo Perin P, Gruden G (2004)
Il sistema MCP-1/CCR2 nelle cellule mesangiali umane: modulazione da stretch e ruolo nell?espressione di ICAM-1.
https://iris.unito.it/handle/2318/119491

Setti G, Gruden G, Hayward A, Sugden D, Gnudi L, Viberti GC (2003)
Rosiglitazone prevents stretch-induced monocyte recruitment by inhibiting the NFkB-MCP-1 pathway in human mesangial cells.
https://iris.unito.it/handle/2318/119276

Gnudi L, Gruden G, Viberti GC (2003)
Pathogenesis of Diabetic Nephropathy.
https://iris.unito.it/handle/2318/118843

Gnudi L, Setti G, Gruden G, Hayward A, Sugden D, Buckingham R, Viberti G (2003)
Rosiglitazone prevents stretch-induced monocytes recruitment by inhibiting the NFkB-MCP1 pathway in human mesangial cells.
https://iris.unito.it/handle/2318/120771

Gnudi L, Gruden G, Burt DJ, Hayward A, Thomas S, Viberti GC (2003)
Mechanical stretch and cytokines upregulate vascular endothelial growth factor and its receptors in glomerular epithelial cells in vitro.
https://iris.unito.it/handle/2318/120772

Gruden G, Setti G, Hayward A, Sugden D, Buckingham R, Gnudi L, Viberti GC (2003)
Rosiglitazone prevents stretch-induced monocyte recruitment by inhibiting the NFkB MCP1 pathway in human mesangial cells.
https://iris.unito.it/handle/2318/120773

GNUDI L, VIBERTI G, RAIJ L, RODRIGUEZ V, BURT D, CORTES P, HARTLEY B, THOMAS S, MAESTRINI S, G GRUDEN (2003)
GLUT-1 overexpression: Link between hemodynamic and metabolic factors in glomerular injury?
https://iris.unito.it/handle/2318/36692

GRUDEN G, ARAF S, ZONCA S, BURT D, THOMAS S, GNUDI L, VIBERTI G (2003)
IGF-I induces vascular endothelial growth factor in human mesangial cells via a Src-dependent mechanism.
https://iris.unito.it/handle/2318/38325

D J BURT, G GRUDEN, S M THOMAS, P TUTT, C DELL', ANNA, G C VIBERTI, L GNUDI (2003)
P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells.
https://iris.unito.it/handle/2318/42579

Hayward A, Burt D, Gruden G, Thomas S, Viberti GC, Gnudi G (2003)
Mechanical Stretch and Cytokines Upregulate Vascular Endothelial Growth Factor and its Receptors in Glomerular Epithelial Cells, In Vitro.
https://iris.unito.it/handle/2318/119401

Hayward A, Setti G, Thomas S, Gnudi L, Viberti G, Gruden G (2002)
Stretch up-regulates VEGF in murine glomerular epithelial cells via a PKC-independent mechanism.
https://iris.unito.it/handle/2318/119102

Gruden G, Setti G, Gnudi L, Viberti GC (2002)
Mechanical stretch induces MCP-1 production in human mesangial cells via a NF-kB-dependent mechanism.
https://iris.unito.it/handle/2318/118420

Gruden G, Invitti C, Viberti GC (2002)
Strategie terapeutiche nel trattamento dell'insulino-resistenza.
https://iris.unito.it/handle/2318/121795

Burt D, Gruden G, Thomas S, Viberti G, Gnudi L (2002)
P38-MAPK mediates hexosamine-induced TGF-b1 mRNA expression in human mesangial cells.
https://iris.unito.it/handle/2318/118846

Gruden G, Setti G, Hayward A, Gnudi L, Viberti G (2002)
Rosiglitazone prevents stretch-induced MCP-1 production in human mesangial cells.
https://iris.unito.it/handle/2318/119528

Burt D, Gruden G, Thomas S, Tutt P, Viberti G, Gnudi L (2002)
P38-mitogen activated protein kinase mediates hexosamine-induced TGF beta 1 mRNA expression in human mesangial cells.
https://iris.unito.it/handle/2318/119100

Gruden G, Setti G, Hayward A, Gnudi L, Viberti G (2002)
Rosiglitazone prevents stretch-induced MCP-1 production in human mesangial cells.
https://iris.unito.it/handle/2318/119099

Gruden G, Hayward A, Setti G, Gnudi G, Viberti GC (2002)
Stretch upregulates Vascular Endothelial Growth factor in murine glomeurlar epithelial cells via a PKC-independent mechanism.
https://iris.unito.it/handle/2318/118425

Burt D, Gruden G, Thomas S, Viberit GC, Gnudi L (2002)
Hexosamine-induced TGF-b1 mRNA expression is mediated by P38-MAPK in human mesangial cells.
https://iris.unito.it/handle/2318/118422

Araf S, Gruden G, Gnudi L, Thomas S, Burt D, Viberti G (2002)
Insulin growth factor-1 induces vascular endothelial growth factor protein secretion via a Src-dependent mechanism in human mesangial cells.
https://iris.unito.it/handle/2318/118847

Rodriquez V, Gruden G, Gnudi L, Johnson B, Thomas S, Hartley B, Raij L, Viberti GC (2001)
Glut-1 upregulation in glomerular hypertension: implication for diabetic glomerulopathy.
https://iris.unito.it/handle/2318/118723

Gnudi L, Hayward A, Thomas S, Gruden G, Viberti GC (2001)
Mechanical stretch induces reduction in alpha3 beta1 integrins in Glomerular Epithelial Cells in vitro.
https://iris.unito.it/handle/2318/118780

Gruden G, Gnudi L, Rodriguez V, Johnson B, Thomas S, Hartley B, Raij L, Viberti GC (2001)
GLUT1 is upregulated in glomerular hypertension: Possible role in the pathophysiology of diabetic glomerulopathy.
https://iris.unito.it/handle/2318/118781

Burt D, Thomas S, Gruden G, Tutt P, Dell', Anna C, Viberti GC, Gnudi L (2001)
High glucose is necessary for hexosamine-induced TGF-b1 expression in human mesangial cells.
https://iris.unito.it/handle/2318/119236

Burt D, Thomas S, Gruden G, Tutt P, Viberti GC, Gnudi L (2001)
The role of the exosamine pathway in glucose-induced TGF-b1 expression in human mesangial cells.
https://iris.unito.it/handle/2318/118724

Rodriguez V, Thomas S, Burt D, Gruden G, Hartley B, Gnudi L, Viberti G (2000)
Vascular endothelial growth factor receptors are expressed in vitro and ex-vivo by human mesangial cells.
https://iris.unito.it/handle/2318/118783

Gruden G, Zonca S, Hayward A, Thomas S, Gnudi L, Viberti (2000)
p38 MAP kinase mediates TGF-b1-induced fibronectin production in human mesangial cells.
https://iris.unito.it/handle/2318/119568

THOMAS S, VANUYSTEL J, GRUDEN G, RODRÍGUEZ V, BURT D, GNUDI L, HARTLEY B, VIBERTI G (2000)
Vascular endothelial growth factor receptors in human mesangium in vitro and in glomerular disease.
https://iris.unito.it/handle/2318/35017

Gruden G, Thomas S, Burt D, Zonca S, Gnudi L, Viberti G (2000)
IGF-I induces Vascular Endothelial Growth Factor gene expression and protein secretion in human mesangial cells.
https://iris.unito.it/handle/2318/118782

Gruden G (2000)
ROLE OF THE HAEMODYNAMIC INSULT IN THE PATHOGENESIS OF DIABETIC NEPHROPATHY: A NEW HYPOTHESIS.
https://iris.unito.it/handle/2318/120760

Burt DJ, Rahman A, Thomas SM, Gruden G, Gnudi L, Viberti G (2000)
Vascular Endothelial Growth Factor receptors are expressed in glomerular epithelial cells in vitro.
https://iris.unito.it/handle/2318/120098

Cavallo-Perin P, Lupia E, Gruden G, Olivetti C, De Martino A, Cassader M, Furlani D, Servillo L, Quagliuolo L, Iorio E, Boccellino MR, Montrucchio G, Camussi G (2000)
Increased blood levels of platelet-activating factor ininsulin-dependent diabetic patients with microalbuminuria.
https://iris.unito.it/handle/2318/108871

G GRUDEN, ZONCA S, HAYWARD A, THOMAS S, MAESTRINI S, GNUDI L, VIBERTI GC (2000)
Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent.
https://iris.unito.it/handle/2318/38150

P CAVALLO PERIN, GRUDEN G , GIUNTI S , ARNALDI L , CASSADER M , GAMBINO R , PAGANO G (2000)
Apolipoprotein H is increased in type 2 diabetic patients with microalbuminuria.
https://iris.unito.it/handle/2318/37809

Gruden G, Zonca S, Hayward A, Thomas S, Gnudi L, Viberti GC (1999)
P38-MAPK mediates stretch-induced fibronectin producton in human mesangial cells.
https://iris.unito.it/handle/2318/119569

GRUDEN G, THOMAS S, BURT D, ZHOU W, CHUSNEY G, GNUDI L, VIBERTI G (1999)
Interaction of angiotensin II and mechanical stretch on vascular endothelial growth factor production by human mesangial cells.
https://iris.unito.it/handle/2318/40342

Thomas S, Gruden G, Burt D, Chusney G, Viberti GC (1998)
Vascular endothelial growth factor production by human mesangial cells.
https://iris.unito.it/handle/2318/120636

Gruden G, Thomas S, Burt D, Sacks S, Gnudi L, Viberti GC (1998)
Mechanical stretch induces TGF-b1 and type II-TGF-b1 receptor in human mesangial cells.
https://iris.unito.it/handle/2318/120886

Gruden G, Thomas S, Burt D, Sacks S, Viberti GC (1998)
Interaction of angiotensin II and stretch in the production of vascular endothelial growth factor (VEGF) by human mesangial cells.
https://iris.unito.it/handle/2318/118849

Burt D, Thomas S, Chusney G, Gruden G, Gnudi L, Viberti GC (1998)
Platelets: an important source of circulating vascular endothelial growth factor.
https://iris.unito.it/handle/2318/118848

Thomas S, Burt D, Vanuystel J, Gruden G, Gnudi L, Viberti GC (1998)
Glucose-induced TGF-b1 in skin fibroblasts from type 1 diabetic patients with diabetic nephropathy.
https://iris.unito.it/handle/2318/120885

BAZZAN M, GRUDEN G, STELLA S, VACCARINO A, TAMPONI G, OLIVETTI C, GIUNTI S, P CAVALLO PERIN (1998)
Microalbuminuria in IDDM is associated with increased expression of monocyte procoagulant activity.
https://iris.unito.it/handle/2318/40190

Cavallo-Perin P, Gruden G, Olivetti C (1998)
Microalbuminuria and cardiovascular risk.
https://iris.unito.it/handle/2318/120761

Gruden G, Thomas S, Burt D, Sacks S, Gnudi L, Viberti GC (1998)
Mechanical stretch induces TGF-b1 and type II-TGF-b1 receptor in human mesangial cells.
https://iris.unito.it/handle/2318/118725

Gruden G, Thomas S, Burt D, Lane S, Chusney G, Sacks S, Viberti GC (1997)
Mechanical Stretch Induces Vascular Permeability Factor (VPF) in Human Mesangial Cells: Mechanisms of Signal Transduction.
https://iris.unito.it/handle/2318/118785

Thomas SM, Gruden G, Viberti GC (1997)
Haemodynamic and metabolic promoters of microalbuminuria.
https://iris.unito.it/handle/2318/121087

GRUDEN G, THOMAS S, BURT D, LANE S, CHUSNEY G, SACKS S, VIBERTI G (1997)
Mechanical stretch induces vascular permeability factor in human mesangial cells: mechanisms of signal transduction.
https://iris.unito.it/handle/2318/32908

Thomas S, J Vanuysel, Gruden G, Burt D, Sack S, Viberti GC (1997)
Vascular endothelial growth factor (VEGF) induces the proliferation of human mesangial cells.
https://iris.unito.it/handle/2318/120099

Gruden G, Olivetti C, Montrucchio G, Lupia E, Camussi G, Cavallo Perin P (1997)
Increased levels of platelet-activating factor in insulin-dependent diabetic patients with microalbuminuria.
https://iris.unito.it/handle/2318/118784

Gruden G, Thomas S, Burt D, Chusney G, Sacks S, Viberti GC (1997)
Angiotensin II and mechanical stretch independently induces Vascular Permeability Factor (VPF) in human mesangial cells.
https://iris.unito.it/handle/2318/119237

Gruden G, De Cosmo S, Viberti GC (1997)
Obesità e sindrome plurimetabolica: legami molecolari.
https://iris.unito.it/handle/2318/121796

Bruno A, Fornengo P, Gruden G, CavalloPerin P, Cassader M, Milani S, Poggi G, Pagano G (1997)
Serum glucose, insulin, C-peptide and plasma glucagon response to oral glucose after intravenous injection of different glucocorticoids at increasing doses in man.
https://iris.unito.it/handle/2318/118602

Thomas S, Gruden G, Burt D, Chusney G, Viberti GC (1997)
Sustained glucose induced TGF-b1 production in skin fibroblasts from IDDM patients with diabetic nephropathy.
https://iris.unito.it/handle/2318/118658

GRUDEN G, OLIVETTI C, P CAVALLO PERIN, BAZZAN M, STELLA S, TAMPONI G, PAGANO G (1997)
Activated protein C resistance in type I diabetes.
https://iris.unito.it/handle/2318/40868

GRUDEN G, OLIVETTI C, TALIANO C, FURLANI D, GAMBINO R, PAGANO G, CAVALLO-PERIN P (1996)
Lipoprotein(a) after acute exercise in healthy subjects.
https://iris.unito.it/handle/2318/29820

MORMILE A, VEGLIO M, GRUDEN G, GIROTTO M, ROSSETTO P, D', ESTE P, CAVALLO-PERIN P (1996)
Physiological inhibitors of blood coagulation and prothrombin fragment F 1 + 2 in type 2 diabetic patients with normoalbuminuria and incipient nephropathy.
https://iris.unito.it/handle/2318/29818

Thomas S, Gruden G, Burt D, Chusney G, Viberti GC (1996)
High glucose induces Vascular Permeability Factor protein secretion in cultured human mesangial cells.
https://iris.unito.it/handle/2318/119570

Gruden G, Thomas S, Sacks S, Viberti GC (1996)
Mechanical stretch induces Vascular Permeability Factor gene expression and protein secretion in human mesangial cells.
https://iris.unito.it/handle/2318/119238

Gruden G, Thomas S, Sacks S, Viberti GC (1996)
Mechanical stretch induces TGF-b1 gene expression and protein secretion in human mesangial cells.
https://iris.unito.it/handle/2318/118659

Gruden G, Thomas S, Sacks S, Viberti GC (1996)
Mechanical stretch induces Vascular Permeability Factor gene expression and protein secretion in human mesangial cells.
https://iris.unito.it/handle/2318/118660

GRUDEN G, P CAVALLO PERIN, OLIVETTI C, REPETTI E, SIVIERI R, BRUNO A, PAGANO G (1995)
Albumin excretion rate levels in non-diabetic offspring of NIDDM patients with and without nephropathy.
https://iris.unito.it/handle/2318/40867

Veglio M, Gruden G, Mormile A, Girotto M, Rossetto P, D', Este P, Cavallo-Perin P (1995)
Anticoagulant protein C activity in non-insulin-dependent diabetic patients with normoalbuminuria and microalbuminuria.
https://iris.unito.it/handle/2318/120831

Olivetti C, Gruden G, Bazzan M, Stella S, Cavallo Perin P (1995)
Microalbuminuria in insulin-dependent diabetes is associated with monocyte procoagulant activity.
https://iris.unito.it/handle/2318/118786

Veglio M, Mormile A, Gruden G, Girotto M, Rossetto P, Cavallo Perin P (1995)
Coagulation inhibitors in type 2 diabetic patients with and without microalbuminuria.
https://iris.unito.it/handle/2318/119267

Thomas S, Gruden G, Lane S, Viberti GC (1995)
Glucose-induced vascular permeability factor (VPF) gene expression shows individual variability in cultured skin fibroblasts.
https://iris.unito.it/handle/2318/118726

Gruden G, Pagano G, Romagnoli R, Frezet D, Olivetti C, Cavallo-Perin P (1995)
Thrombomodulin levels in insulin-dependent diabetic patients with microalbuminuria.
https://iris.unito.it/handle/2318/120830

Bruno A, Carucci P, Cassader M, Cavallo-Perin P, Gruden G, Olivetti C, Pagano G (1994)
Serum glucose, insulin and C-peptide response to oral glucose after intravenous administration of hydrocortisone and methylprednisolone in man.
https://iris.unito.it/handle/2318/120829

Gruden G, Cavallo-Perin P, Bazzan M, Stella S, Vuolo A, Pagano G (1994)
PAI-1 and factor VII activity are higher in IDDM patients with microalbuminuria.
https://iris.unito.it/handle/2318/120416

Olivetti C, Gruden G, Veglio M, Mormile A, Cassader M, Cavallo Perin P, Pagano G (1994)
Lipoprotein(a) and insulin treatment in non insulin dependent diabetic patients.
https://iris.unito.it/handle/2318/121341

Gruden G, Veglio M, Cavallo-Perin P, Olivetti C, Mormile A, Cassader M, Pagano G (1994)
Lipoprotein(a) in non-insulin-dependent diabetic patients with normo- and microalbuminuria.
https://iris.unito.it/handle/2318/120827

Gruden G, Censon A, Olivetti C, Cavallo Perin P (1994)
Microalbuminuria and plasma endothelin-1 in non insulin dependent diabetes mellitus.
https://iris.unito.it/handle/2318/121088

Veglio M, Mormile A, Girotto P, Rossetto P, Autino R, Gruden G, Cavallo Perin P (1994)
Anticoagulant protein C in type II diabetic patients with and without microalbuminuria.
https://iris.unito.it/handle/2318/121339

Gruden G, Veglio M, Cavallo-Perin P, Olivetti C, Mormile A, Cassader M, Pagano G (1994)
Lipoprotein(a) and insulin treatment in NIDDM patients.
https://iris.unito.it/handle/2318/120263

Cavallo Perin P, Gruden G (1994)
Trattamento del paziente diabetico in caso di intervento chirurgico.
https://iris.unito.it/handle/2318/119526

Cavallo Perin P, Gruden G (1994)
Coma nel diabetico.
https://iris.unito.it/handle/2318/121883

Gruden G, Cavallo-Perin P, Romagnoli R, Ruiu G, Pagano G (1994)
Plasma beta-thromboglobulin and platelet factor 4 are not increased in insulin-dependent diabetic patients with microalbuminuria.
https://iris.unito.it/handle/2318/120828

Gruden G, Olivetti C, Romagnoli R, Frezet D, Cavallo Perin P, Pagano G (1994)
Trombomodulin is increased in microalbuminuric insulin dependent diabetic patients.
https://iris.unito.it/handle/2318/120353

Gruden G, Cavallo-Perin P, Romagnoli R, Olivetti C, Frezet D, Pagano G (1994)
Prothrombin fragment 1 + 2 and antithrombin III-thrombin complex in microalbuminuric type 2 diabetic patients.
https://iris.unito.it/handle/2318/120417

CAVALLO-PERIN P, BRUNO A, SCAGLIONE L, GRUDEN G, CASSADER M, PAGANO G (1993)
Feedback inhibition of insulin and glucagon secretion by insulin is altered in abdominal obesity with normal or impaired glucose tolerance.
https://iris.unito.it/handle/2318/29739

Gruden G, Bazzan M, Stella S, Pagano G, Pileri A, Cavallo-Perin P (1993)
Microalbuminuria in insulin-dependent diabetes is associated with high levels of prothrombin fragment 1 + 2.
https://iris.unito.it/handle/2318/120418

Gruden G, Cavallo Perin P, Bazzan M, Stella S, Bruno A, Pagano G (1993)
Haemostatic alterations in microalbuminuric insulin dependent diabetic patient.
https://iris.unito.it/handle/2318/119269

CAVALLO-PERIN P, CHIAMBRETTI A, CALEFATO V, TOMALINO M, CECCHINI G, GRUDEN G, PAGANO G (1992)
Urinary excretion of glycated albumin in insulin-dependent diabetic patients with micro- and macroalbuminuria.
https://iris.unito.it/handle/2318/29830

CAVALLO-PERIN P, BRUNO A, CASSADER M, CESCO L, GRUDEN G, PAGANO G (1992)
The glucoregulatory and antilipolytic actions of insulin in abdominal obesity with normal or impaired glucose tolerance: an in vivo and in vitro study.
https://iris.unito.it/handle/2318/29740

Gruden G, Pasetti V, Estivi P, Bruno A, Pagano G, Cavallo Perin P (1992)
Albumin excretion rate in non diabetic offspring of type 2 diabetic patients.
https://iris.unito.it/handle/2318/120422

GRUDEN G, BRUNO A, ESTIVI P, FERRERO R, PAGANO G, CAVALLO-PERIN P (1991)
Albumin excretion rate is not increased in atherosclerotic patients with peripheral vascular disease.
https://iris.unito.it/handle/2318/29700

Tag: Diabetic nephropathy, Diabetes, Diabetic Complications, Albuminuria, Glomeruli, Kidney, Podocytes, Mesangial Cells, Endocannabinoids, miRNA, Inflammation, Exososomes

Last update: 13/09/2015 23:55
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