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Laboratory of Diabetes and Metabolic Diseases

 

PI/CoordinatorProf. Roberto Gambino 

  • Mechanisms of micro/macrovascular complications of diabetes 
  • Mechanisms of intercellular communication in diabetic nephropathy and other chronic glomerulopathy
  • Biomarkers of renal and cardiovascular complications of diabetes

  • Musso G, Sircana A, Saba F, Cassader M, Gambino R. Assessing the risk of ketoacidosis due to sodium-glucose cotransporter (SGLT)-2 inhibitors in patients with type 1 diabetes: A meta-analysis and meta-regression. Plos Med 2020, 17(12): 1-31, e1003461
  • Musso G, Saba F, Cassader M, Gambino R. Diabetic ketoacidosis with SGLT2 inhibitors. British Medical Journal, 2020, 371: m4147.
  • Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis. Musso G, Cassader M, Paschetta E, Gambino R. Gastroenterology. 2018 Aug;155(2):282-302.e8. doi: 10.1053/j.gastro.2018.06.031. Epub 2018 Jun 12. Review.
  • MERTK rs4374383 variant predicts incident nonalcoholic fatty liver disease and diabetes: role of mononuclear cell activation and adipokine response to dietary fat. Musso G, Cassader M, De Michieli F, Paschetta E, Pinach S, Saba F, Bongiovanni D, Framarin L, Berrutti M, Leone N, Corvisieri S, Parente R, Molinaro F, Sircana A, Bo S, Gambino R. Hum Mol Genet. 2017 May 1;26(9):1747-1758. doi: 10.1093/hmg/ddw400. PMID: 29906416
  • TM6SF2 rs58542926 variant affects postprandial lipoprotein metabolism and glucose homeostasis in NAFLD. Musso G, Cipolla U, Cassader M, Pinach S, Saba F, De Michieli F, Paschetta E, Bongiovanni D, Framarin L, Leone N, Berrutti M, Rosina F, Corvisieri S, Molinaro F, Sircana A, Gambino R. J Lipid Res. 2017 Jun;58(6):1221-1229. doi: 10.1194/jlr.M075028. Epub 2017 Feb 27. PMID: 28242789.

  • EURODIAB Prospective Complication Study
  • TESEO Study (Dipartimenti di Eccellenza): Precision medicine in cardiometabolic diseases 
  • Italian Society of Diabetes: “Role of tunneling nanotubes in the interaction between podocytes and glomerular parietal cells in diabetic nephropathy”.

  

Last update: 18/05/2023 12:43
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