• Prof. Anna Sapino, Lead
• Prof. Caterina Marchiò, co-lead
• Dr. Enrico Berrino Post-Doctoral fellow
• Dr. Eliano Cascardi, PhD student
• Sara Erika Bellomo, Post-Doctoral fellow, research contract in colleboartion with FPO-IRCCS
• Anita Chesta, technician, research contract in colleboartion with FPO-IRCCS

Anatomia Patologica, I piano
FPO-IRCCS Istituto di Candiolo
caterina.marchio@unito.it
Tel: 0119933465

• Prof.ssa Anna Sapino
• Prof.ssa Caterina Marchiò

• Morphological characterization and in situ immunophenotypic profiling of tumor lesions
• Molecular profiling of tumoral and non-tumoral tissues with next generation sequencing methods (from targeted panels to exome and genome-wide analyses)
• Study of the determinants of the pre-analytical phase in Pathology
• Development of clinical studies aimed at validating new diagnostic methods

• What are the standard methods to detect NTRK fusions in daily practice and clinical research?
• Just The Woman I Am - Caterina Marchiò
• Mammella HER2 low: un nuovo scenario
• NTRK CONNECT - Update from ESMO 2019
• WG ANATOMIA PAT. E BIOBANCHE | Matrice essenziale nella ricerca

• List of publications of the last 3 years 

1. Real-world histopathological approach to malignancy of undefined primary origin (MUO) to diagnose cancers of unknown primary (CUPs). Pisacane A, Cascardi E, Berrino E, Polidori A, Sarotto I, Casorzo L, Panero M, Boccaccio C, Verginelli F, Benvenuti S, Dellino M, Comoglio P, Montemurro F, Geuna E, Marchiò C, Sapino A.
   Virchows Arch. 2022 Nov 8:1-13. doi: 10.1007/s00428-022-03435-z. Online ahead of print.
   PMID: 36346458 Free PMC article.
2. Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas.
   Berrino E, Annaratone L, Bellomo SE, Ferrero G, Gagliardi A, Bragoni A, Grassini D, Guarrera S, Parlato C, Casorzo L, Panero M, Sarotto I, Giordano S, Cereda M, Montemurro F, Ponzone R, Crosetto N, Naccarati A, Sapino A, Marchiò C. Genome Med. 2022 Aug 29;14(1):98. doi: 10.1186/s13073-022-01104-z. PMID: 36038884 Free PMC article.
3. Tissue Fixation with a Formic Acid-Deprived Formalin Better Preserves DNA Integrity over Time.
   Berrino E, Annaratone L, Detillo P, Grassini D, Bragoni A, Sapino A, Bussolati B, Bussolati G, Marchiò C.
   Pathobiology. 2022 Jul 20:1-11. doi: 10.1159/000525523. Online ahead of print.
   PMID: 35858535
4. The Tumor-Specific Expression of L1 Retrotransposons Independently Correlates with Time to Relapse in Hormone-Negative Breast Cancer Patients.
   Berrino E, Miglio U, Bellomo SE, Debernardi C, Bragoni A, Petrelli A, Cascardi E, Giordano S, Montemurro F, Marchiò C, Venesio T, Sapino A.
   Cells. 2022 Jun 16;11(12):1944. doi: 10.3390/cells11121944.
   PMID: 35741073 Free PMC article.
5. Collision of germline POLE and PMS2 variants in a young patient treated with immune checkpoint inhibitors.
   Berrino E, Filippi R, Visintin C, Peirone S, Fenocchio E, Farinea G, Veglio F, Aglietta M, Sapino A, Cereda M, Visintin R, Pasini B, Marchiò C.
   NPJ Precis Oncol. 2022 Mar 8;6(1):15. doi: 10.1038/s41698-022-00258-8.
   PMID: 35260767 Free PMC article.

• AIRC Investigator Grant “A GENOMIC-DRIVEN DIAGNOSIS TO DELIVER BESPOKE THERAPEUTIC STRATEGIES IN HER2-LOW BREAST CANCER PATIENTS”
• AIRC 5x1000 project “Insights into the evolving heterogeneity of metastatic colorectal cancer: from mechanisms to therapies”