Study of the features of latent infection and pulmonary/extrapulmonary tuberculous disease;
In collaboration with the Pharmacology and Pharmacogenetics Laboratory of the University of Turin (Prof. Antonio D'Avolio, Prof. Jessica Cusato) study of plasma, intracellular and tissue concentrations of antimycobacterial drugs
In collaboration with the Pharmacology and Pharmacogenetics Laboratory of the University of Turin (Prof. Antonio D'Avolio, Prof. Jessica Cusato) study of pharmacogenetics in patients with Mycobacterium tuberculosis disease or non-tuberculous mycobacteria (NTM);
Study of the clinical characteristics and response to therapy in patients with NTM lung disease (IRENE Registry);
Study of serum and imaging biomarkers for the diagnosis and follow up of patients with NTM infection.
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PMID: 34784880. Stroffolini G, Guastamacchia G, Audagnotto S, Atzori C, Trunfio M, Nigra M, Di Stefano A, Di Perri G, Calcagno A. Low cerebrospinal fluid Amyloid-βeta 1-42 in patients with tuberculous meningitis. BMC Neurol. 2021 Nov 16;21(1):449. doi: 10.1186/s12883-021-02468-2.
PMID: 33539932. Trentalange A, Borgogno E, Motta I, Antonucci M, Pirriatore V, Costa C, Rossi G, Barco A, De Nicolò A, Piccioni P, D'Avolio A, Bonora S, Di Perri G, Calcagno A.Rifampicin and Isoniazid Maximal Concentrations are Below Efficacy-associated Thresholds in the Majority of Patients: Time to Increase the Doses? Int J Antimicrob Agents. 2021 Mar;57(3):106297. doi: 10.1016/j.ijantimicag.2021.106297.
PMID: 30779340. Calcagno A, Cusato J, Sekaggya-Wiltshire C, von Braun A, Motta I, Turyasingura G, Castelnuovo B, Fehr J, Di Perri G, Lamorde M The Influence of Pharmacogenetic Variants in HIV/Tuberculosis Coinfected Patients in Uganda in the SOUTH Study.. Clin Pharmacol Ther. 2019 Aug;106(2):450-457. doi: 10.1002/cpt.1403
PMID: 29226732. Motta I, Calcagno A, Bonora S. Pharmacokinetics and pharmacogenetics of anti-tubercular drugs: a tool for treatment optimization? Expert Opin Drug Metab Toxicol. 2018 Jan;14(1):59-82. doi: 10.1080/17425255.2018.1416093.
PMID: 30151192. Aliberti S, Codecasa LR, Gori A, Sotgiu G, Spotti M, Di Biagio A, Calcagno A, Nardini S, Assael BM, Tortoli E, Besozzi G, Ferrarese M, Matteelli A, Girardi E, De Lorenzo S, Seia M, Gramegna A, Del Prato B, Terranova L, Oriano M, Sverzellati N, Mirsaeidi M, Chalmers JD, Haworth CS, Loebinger MR, Aksamit T, Winthrop K, Ringshausen FC, Previdi G, Blasi F; IRENE Network. The Italian registry of pulmonary non-tuberculous mycobacteria - IRENE: the study protocol. Multidiscip Respir Med. 2018 Aug 9;13(Suppl 1):33. doi: 10.1186/s40248-018-0141-8.
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Mycobacteria study group of the Italian Society of Infectious Diseases and Tropical Medicine "MYGRO" (https://www.simit.org/attivita/gruppi-di-studio/126-tuberculosi-mygro)
IRENE national registry (https://www.registroirene.it)
Participation in TB-Net (https://www.tbnet.eu) and NTM-Net (http://www.ntm-net.org)
