In collaboration with the Pharmacology and Pharmacogenetics Laboratory of the University of Turin (Prof. Antonio D'Avolio, Prof. Jessica Cusato) study of clinical pharmacology of antiretrovirals in the real setting with a particular focus on the efficacy, interindividual variability, drug-drug interactions, tailored approached to antiretroviral therapy;
Study of the clinical impact of plasma, intracellular and tissue concentrations of antiretroviral drugs;
Screening and evaluation of comorbidity burden in people living with HIV;
Study of pharmacological determinants of antiretroviral forgiveness;
Study of patients with multi-drug resistant HIV infection (Registro Prestigio);
Study of patients over-65 years old with HIV infection (Coorte Geppo);
Study of inflammatory plasma biomarkers during follow-up of patients with HIV.
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PMID: 36115063. Inflammation and intracellular exposure of dolutegravir, darunavir, tenofovir and emtricitabine in people living with HIV. Ferrara, M., Cusato, J., Salvador, E.. Trentalange, A., Alcantarini, C., Trunfio, M., Cannizzo, E.S., Bono, V., Nozza, S., De Nicolò, A. Ianniello, A., De Vivo, E., D'Avolio, A., Di Perri, G., Bonora, S., Marchetti, G., Calcagno, A. Br J Clin Pharmacol 2023 Mar;89(3):1020-1026. doi: 10.1111/bcp.15538.
PMID: 34644336. Durability of Integrase STrand Inhibitor (InSTI)-based regimen in geriatric people living with HIV in the GEPPO cohort. Emanuele Focà, Andrea Calcagno, Stefano Calza, Stefano Renzetti, Annacarla Chiesa, Matteo Siano, Giuseppe De Socio, Stefania Piconi, Giancarlo Orofino, Giordano Madeddu, Anna Maria Cattelan, Silvia Nozza, Micol Ferrara, Jovana Milic, Benedetto Maurizio Celesia, Francesco Castelli, Giovanni Guaraldi. PLoS One 2021 Oct 13;16(10):e0258533. doi: 10.1371/journal.pone.0258533. eCollection 2021
PMID: 32211890. Antiretroviral concentrations in the presence and absence of valproic acid A Calcagno, J Cusato, M Ferrara, A De Nicolò, A Lazzaro, A Manca, A D'Avolio, G Di Perri, S Bonora. J Antimicrob Chemother 2020 Jul 1;75(7):1969-1971. doi: 10.1093/jac/dkaa094.
PMID: 32694413. Antiretroviral drug concentrations in brain tissue of adult decedents Micol Ferrara, Namandjé N Bumpus, Qing Ma, Ronald J Ellis, Virawudh Soontornniyomkij, Jerel A Fields, Ajay Bharti, Cristian L Achim, David J Moore, Scott L Letendre. AIDS. 2020 Nov 1;34(13):1907-1914. doi: 10.1097/QAD.0000000000002628
PMID: 36708743. Residual phenotypic susceptibility to doravirine in multidrug-resistant HIV-1 from subjects enrolled in the PRESTIGIO Registry. Francesco Saladini, Federica Giammarino, Franco Maggiolo, Micol Ferrara, Giovanni Cenderello, Benedetto M Celesia, Ferdinando Martellotta, Vincenzo Spagnuolo, Giulio M Corbelli, Nicola Gianotti, Maria M Santoro, Stefano Rusconi, Maurizio Zazzi, Antonella Castagna; PRESTIGIO Study Group. Int J Antimicrob Agents 2023 Jan 25;61(3):106737. doi: 10.1016/j.ijantimicag.2023.106737.
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Coorte GEPPO (GEriatric Patients living with HIV/AIDS cOhort (GEPPO), (https://penta-id.org/hiv/geppo)
Registro nazionale PRESTIGIO (https://www. www.registroprestigio.com)
