Department of Medical Sciences

Research products

All my research products

Selected research products

Lift the curtain on long non-coding RNAs in hematological malignancies: Pathogenic elements and potential targets
2022-01-01 Iannello A.; Ciarrocchi A.; Fragliasso V.; Vaisitti T. https://iris.unito.it/handle/2318/1858328

Adult-onset CblC deficiency: a challenging diagnosis involving different adult clinical specialists
2022-01-01 Kalantari S.; Brezzi B.; Bracciama V.; Barreca A.; Nozza P.; Vaisitti T.; Amoroso A.; Deaglio S.; Manganaro M.; Porta F.; Spada M. https://iris.unito.it/handle/2318/1849385

LINC00152 expression in normal and Chronic Lymphocytic Leukemia B cells
2022-01-01 Matis S.; Rossi M.; Brondolo L.; Cardillo M.; Reverberi D.; Massara R.; Colombo M.; Ibatici A.; Angelucci E.; Vaisitti T.; Bruno S.; Fabris S.; Neri A.; Gentile M.; Morabito F.; Cutrona G.; Briata P.; Gherzi R.; Fais F. https://iris.unito.it/handle/2318/1858315

Novel Approaches for the Treatment of Patients with Richter’s Syndrome
2022-01-01 Iannello A.; Deaglio S.; Vaisitti T. https://iris.unito.it/handle/2318/1858332

Validation of a Simple, Rapid, and Cost-Effective Method for Acute Rejection Monitoring in Lung Transplant Recipients
2022-01-01 Sorbini, Monica; Togliatto, Gabriele; Mioli, Fiorenza; Simonato, Erika; Marro, Matteo; Cappuccio, Margherita; Arruga, Francesca; Caorsi, Cristiana; Mansouri, Morteza; Magistroni, Paola; Gambella, Alessandro; Delsedime, Luisa; Papotti, Mauro Giulio; Solidoro, Paolo; Albera, Carlo; Boffini, Massimo; Rinaldi, Mauro; Amoroso, Antonio; Vaisitti, Tiziana; Deaglio, Silvia https://iris.unito.it/handle/2318/1871666

A new taxonomy for splenic marginal zone lymphoma
2022-01-01 Deaglio S.; Vaisitti T. https://iris.unito.it/handle/2318/1858335

Synergistic efficacy of the dual PI3K-δ/γ inhibitor duvelisib with the Bcl-2 inhibitor venetoclax in Richter syndrome PDX models
2021-01-01 Iannello A.; Vitale N.; Coma S.; Arruga F.; Chadburn A.; Di Napoli A.; Laudanna C.; Allan J.N.; Furman R.R.; Pachter J.A.; Deaglio S.; Vaisitti T. https://iris.unito.it/handle/2318/1796033

A novel COLEC10 mutation in a child with 3MC syndrome
2021-01-01 Martina Migliorero, Silvia Kalantari, Valeria Bracciamà, Monica Sorbini, Francesca Arruga, Licia Peruzzi, Elisa Biamino, Antonio Amoroso, Tiziana Vaisitti, Silvia Deaglio https://iris.unito.it/handle/2318/1849383

The frequency of rare and monogenic diseases in pediatric organ transplant recipients in Italy
2021-01-01 Vaisitti, Tiziana; Peritore, Daniela; Magistroni, Paola; Ricci, Andrea; Lombardini, Letizia; Gringeri, Enrico; Catalano, Silvia; Spada, Marco; Sciveres, Marco; Di Giorgio, Angelo; Limongelli, Giuseppe; Varrenti, Marisa; Gerosa, Gino; Terzi, Amedeo; Napoleone, Carlo Pace; Amodeo, Antonio; Ragni, Luca; Strologo, Luca Dello; Benetti, Elisa; Fontana, Iris; Testa, Sara; Peruzzi, Licia; Mitrotti, Adele; Abbate, Serena; Comai, Giorgia; Gotti, Eliana; Schiavon, Marco; Boffini, Massimo; De Angelis, Daniele; Bertani, Alessandro; Pinelli, Domenico; Torre, Massimo; Poggi, Camilla; Deaglio, Silvia; Cardillo, Massimo; Amoroso, Antonio https://iris.unito.it/handle/2318/1800618

HLA and AB0 Polymorphisms May Influence SARS-CoV-2 Infection and COVID-19 Severity
2021-01-01 Amoroso, Antonio; Magistroni, Paola; Vespasiano, Francesca; Bella, Antonino; Bellino, Stefania; Puoti, Francesca; Alizzi, Silvia; Vaisitti, Tiziana; Boros, Stefano; Grossi, Paolo Antonio; Trapani, Silvia; Lombardini, Letizia; Pezzotti, Patrizio; Deaglio, Silvia; Brusaferro, Silvio; Cardillo, Massimo https://iris.unito.it/handle/2318/1760925

B Cell Receptor signaling and genetic lesions in TP53 and CDKN2A/CDKN2B cooperate in Richter Transformation
2021-01-01 Chakraborty, Supriya; Martines, Claudio; Porro, Fabiola; Fortunati, Ilaria; Bonato, Alice; Dimishkovska, Marija; Piazza, Silvano; Yadav, Brijesh S; Innocenti, Idanna; Fazio, Rosa; Vaisitti, Tiziana; Deaglio, Silvia; Zamò, Alberto; Dimovski, Aleksandar J; Laurenti, Luca; Efremov, Dimitar G https://iris.unito.it/handle/2318/1796037

ROR1 targeting with the antibody-drug conjugate VLS-101 is effective in Richter syndrome patient–derived xenograft mouse models
2021-01-01 Vaisitti T.; Arruga F.; Vitale N.; Lee T.-T.; Ko M.; Chadburn A.; Braggio E.; Di Napoli A.; Iannello A.; Allan J.N.; Miller L.L.; Lannutti B.J.; Furman R.R.; Jessen K.A.; Deaglio S. https://iris.unito.it/handle/2318/1796031

HLA-DRB1 mismatch-based identification of donor-derived cell free DNA (dd-cfDNA) as a marker of rejection in heart transplant recipients: A single-institution pilot study.
2021-01-01 Monica Sorbini, https://iris.unito.it/handle/2318/1792061

Targeting of the A2A adenosine receptor counteracts immunosuppression in vivo in a mouse model of chronic lymphocytic leukemia
2021-01-01 Arruga, Francesca; Serra, Sara; Vitale, Nicoletta; Guerra, Giulia; Papait, Andrea; Gyau, Benjamin Baffour; Tito, Francesco; Efremov, Dimitar; Vaisitti, Tiziana; Deaglio, Silvia https://iris.unito.it/handle/2318/1760916

USE OF CLINICAL EXOME SEQUENCING IN THE DIAGNOSTIC FLOW OF MONOGENIC KIDNEY DISEASES: THE PIEDMONT EXPERIENCE
2020-01-01 Deaglio, Silvia; Amoroso, Antonio; Roccatello, Dario; Peruzzi, Licia; Fenoglio, Roberta; Rollino, Cristiana; Baldovino, Simone; Cocchi, Enrico; Giachino, Daniela; Pelle, Alessandra; Vanzino, Silvia Bruna; Arruga, Francesca; Bracciamà, Valeria; Kalantari, Silvia; Callegari, Martina; Sorbini, Monica; Vaisitti, Tiziana https://iris.unito.it/handle/2318/1772802

Nampt over-expression recapitulates the braf inhibitor resistant phenotype plasticity in melanoma
2020-01-01 Audrito V.; Messana V.G.; Moiso E.; Vitale N.; Arruga F.; Brandimarte L.; Gaudino F.; Pellegrino E.; Vaisitti T.; Riganti C.; Piva R.; Deaglio S. https://iris.unito.it/handle/2318/1766319

Chronic lymphocytic leukemia
2020-01-01 Vaisitti T.; Arruga F.; Ferrajoli A. https://iris.unito.it/handle/2318/1760920

Clinical exome sequencing is a powerful tool in the diagnostic flow of monogenic kidney diseases: an Italian experience
2020-01-01 Tiziana Vaisitti, Monica Sorbini, Martina Callegari, Silvia Kalantari, Valeria Bracciamà, Francesca Arruga, Silvia Bruna Vanzino, Sabina Rendine, Gabriele Togliatto, Daniela Giachino, Alessandra Pelle, Enrico Cocchi, Chiara Benvenuta, Simone Baldovino, Cristiana Rollino, Roberta Fenoglio, Savino Sciascia, Michela Tamagnone, Corrado Vitale, Giovanni Calabrese, Luigi Biancone, Stefania Bussolino, Silvana Savoldi, Maurizio Borzumati, Vincenzo Cantaluppi, Fabio Chiappero, Silvana Ungari, Licia Peruzzi, Dario Roccatello, Antonio Amoroso, Silvia Deaglio https://iris.unito.it/handle/2318/1761401

NOVEL AND KNOWN MUTATIONS IDENTIFIED BY CLINICAL EXOME SEQUENCING FOR THE DIAGNOSIS OF POLYCYSTIC KIDNEY DISEASE
2020-01-01 Deaglio, Silvia; Amoroso, Antonio; Roccatello, Dario; Peruzzi, Licia; Gianoglio, Bruno; Viglino, Giusto; Bertinetto, Patrizia; Borzumati, Maurizio; Funaro, Loredana; Santi, Sonia; Maroni, Serena; Strampelli, Emanuela; Biancone, Luigi; Leonardi, Gianluca; Calabrese, Giovanni; Berta, Valentina; Vitale, Corrado; Soragna, Giorgio; Gherzi, Maurizio; Tamagnone, Michela; Fenoglio, Roberta; Rollino, Cristiana; Baldovino, Simone; Cocchi, Enrico; Giachino, Daniela; Pelle, Alessandra; Vanzino, Silvia Bruna; Arruga, Francesca; Bracciamà, Valeria; Kalantari, Silvia; Callegari, Martina; Sorbini, Monica; Vaisitti, Tiziana https://iris.unito.it/handle/2318/1772804

Immune response dysfunction in chronic lymphocytic leukemia: Dissecting molecular mechanisms and microenvironmental conditions
2020-01-01 Arruga F.; Gyau B.B.; Iannello A.; Vitale N.; Vaisitti T.; Deaglio S. https://iris.unito.it/handle/2318/1760911

Subcellular characterization of NAD+ biosynthesis in metastatic melanoma by using organelle-specific biosensors
2019-01-01 Gaudino, Federica; Manfredonia, Ilaria; Managò, Antonella; Audrito, Valentina; Raffaelli, Nadia; Vaisitti, Tiziana; Deaglio, Silvia https://iris.unito.it/handle/2318/1711580

Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter's syndrome: therapeutic implications.
2019-01-01 Arruga F, Bracciamà V, Vitale N, Vaisitti T, Gizzi K, Yeomans A, Coscia M, D'Arena G, Gaidano G, Allan JN, Furman RR, Packham G, Forconi F, Deaglio S https://iris.unito.it/handle/2318/1711579

Ectonucleotidases in Blood Malignancies: A Tale of Surface Markers and Therapeutic Targets
2019-01-01 Vaisitti T.; Arruga F.; Guerra G.; Deaglio S. https://iris.unito.it/handle/2318/1760895

The NOTCH Pathway and Its Mutations in Mature B Cell Malignancies
2018-01-01 Arruga, Francesca; Vaisitti, Tiziana; Deaglio, Silvia https://iris.unito.it/handle/2318/1695288

Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma
2018-01-01 Audrito, Valentina; Manago', Antonella; La Vecchia, Sofia; Zamporlini, Federica; Vitale, Nicoletta; Baroni, Gianna; Cignetto, Simona; Serra, Sara; Bologna, Cinzia; Stingi, Aureliano; Arruga, Francesca; Vaisitti, Tiziana; Massi, Daniela; Mandalã , Mario; Raffaelli, Nadia; Deaglio, Silvia https://iris.unito.it/handle/2318/1650477

Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma
2018-01-01 Audrito V.; Manago A.; La Vecchia S.; Zamporlini F.; Vitale N.; Baroni G.; Cignetto S.; Serra S.; Bologna C.; Stingi A.; Arruga F.; Vaisitti T.; Massi D.; Mandala M.; Raffaelli N.; Deaglio S. https://iris.unito.it/handle/2318/1801075

Targeting the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Novel Therapeutic Opportunities
2018-01-01 Andrea Papait, Tiziana Vaisitti, Sara Serra, Valentina Audrito, Francesco Tito, Giulia Guerra, Dimitar G Efremov, Silvia Deaglio https://iris.unito.it/handle/2318/1695290

Targeting the adenosinergic axis in chronic lymphocytic leukemia: A way to disrupt the tumor niche?
2018-01-01 Vaisitti T, Arruga F, Deaglio S. https://iris.unito.it/handle/2318/1678684

Novel richter syndrome xenograft models to study genetic architecture, biology, and therapy responses
2018-01-01 Vaisitti, Tiziana; Braggio, Esteban; Allan, John N.; Arruga, Francesca; Serra, Sara; Zamo, Alberto; Tam, Wayne; Chadburn, Amy; Furman, Richard R.; Deaglio, Silvia https://iris.unito.it/handle/2318/1671369

Mutations in NOTCH1 PEST-domain orchestrate CCL19-driven homing of Chronic Lymphocytic Leukemia cells by modulating the tumor suppressor gene DUSP22
2017-01-01 Francesca, Arruga; Branimir, Gizdic; Bologna, Cinzia; Cignetto, Simona; Buonincontri, Roberta; Serra, Sara; Vaisitti, Tiziana; Katiuscia, Gizzi; Vitale, Nicoletta; Garaffo, Giulia; Mereu, Elisabetta; Fary, Diop; Francesco, Neri; Coscia, Marta; John, Allan; Piva, Roberto; Oliviero, Salvatore; Richard, Furman; Davide, Rossi; Gianluca, Gaidano; Deaglio, Silvia https://iris.unito.it/handle/2318/1621657

Macitentan, a double antagonist of endothelin receptors, efficiently impairs migration and microenvironmental survival signals in chronic lymphocytic leukemia
2017-01-01 Maffei R, Fiorcari S, Vaisitti T, Martinelli S, Benatti S, Debbia G, Rossi D, Zucchini P, Potenza L, Luppi M, Gaidano G, Deaglio S, Marasca R. https://iris.unito.it/handle/2318/1678686

Targeting metabolism and survival in chronic lymphocytic leukemia and richter syndrome cells by a novel NF-κB inhibitor
2017-01-01 Vaisitti, Tiziana; Gaudino, Federica; Ouk, Samedy; Moscvin, Maria; Vitale, Nicoletta; Serra, Sara; Arruga, Francesca; Zakrzewski, Johannes L.; Liou, Hsiou-chi; Allan, John N.; Furman, Richard R.; Deaglio, Silvia https://iris.unito.it/handle/2318/1652566

SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response
2016-01-01 Bologna, Cinzia; Buonincontri, Roberta; Serra, Sara; Vaisitti, Tiziana; Audrito, Valentina; Brusa, Davide; Pagnani, Andrea; Coscia, Marta; D'Arena, Giovanni; Mereu, Elisabetta; Piva, Roberto; Furman, Richard R; Rossi, Davide; Gaidano, Gianluca; Terhorst, Cox; Deaglio, Silvia https://iris.unito.it/handle/2318/1531649

Mutations in NOTCH1 PEST Domain Orchestrate CCL19-Driven Homing of Chronic Lymphocytic Leukemia (CLL) Cells By Modulating the Gene DUSP22
2016-01-01 Arruga, F; Gizdic, B; Bologna, C; Cignetto, S; Buonincontri, R; Serra, S; Vaisitti, T; Vitale, N; Garaffo, G; Mereu, E; Diop, F; Neri, F; Coscia, M; Allan, JN; Piva, R; Oliviero, S; Furman, RR; Rossi, D; Gaidano, G; Deaglio, S https://iris.unito.it/handle/2318/1691085

Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment
2016-01-01 Serra, Sara; Vaisitti, Tiziana; Audrito, Valentina; Bologna, Cinzia; Buonincontri, Roberta; Chen, Shih-Shih; Arruga, Francesca; Brusa, Davide; Coscia, Marta; Jaksic, Ozren; Inghirami, Giorgio; Rossi, Davide; Furman, Richard R.; Robson, Simon C.; Gaidano, Gianluca; Chiorazzi, Nicholas; Deaglio, Silvia https://iris.unito.it/handle/2318/1615830

SLAMF1/CD150 Activates Autophagy in Chronic Lymphocytic Leukemia Cells, Modulating Chemotaxis and Responses to Therapy
2015-01-01 Bologna, C; Buonincontri, R; Serra, S; Vaisitti, T; Audrito, V; Brusa, D; Pagnani, A; Coscia, M; D'Arena, G; Bhavsar, Eb; Furman, Rr; Rossi, D; Gaidano, G; Terhorst, C; Deaglio, S https://iris.unito.it/handle/2318/1617718

Adenosine Signaling Mediates Hypoxic Responses in the Chronic Lymphocytic Leukemia Microenvironment
2015-01-01 Serra, S; Brusa, D; Vaisitti, T; Buonincontri, R; Audrito, V; Coscia, M; Rossi, D; Bhavsar, Eb; Furman, Rr; Gaidano, G; Deaglio, S https://iris.unito.it/handle/2318/1617729

Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia.
2015-01-01 Audrito V; Serra S; Brusa D; Mazzola F; Arruga F; Vaisitti T; Coscia M; Maffei R; Rossi D; Wang T; Inghirami G; Rizzi M; Gaidano G; Garcia JG; Wolberger C; Raffaelli N; Deaglio S. https://iris.unito.it/handle/2318/157289

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.
2015-01-01 Vaisitti T; Audrito V; Serra S; Buonincontri R; Sociali G; Mannino E; Pagnani A; Zucchetto A; Tissino E; Vitale C; Coscia M; Usai C; Pepper C; Gattei V; Bruzzone S; Deaglio S. https://iris.unito.it/handle/2318/157292

Extracellular Nicotinamide Phosphoribosyltransferase (NAMPT) Shapes the CLL Microenvironment Promoting Macrophage M2 Polarization Via a Non-Enzymatic Mechanism
2014-01-01 Audrito, V; Serra, S; Brusa, D; Mazzola, F; Arruga, F; Vaisitti, T; Coscia, M; Maffei, R; Rossi, D; Wang, T; Inghirami, G; Rizzi, M; Gaidano, G; Wolberger, C; Raffaelli, N; Deaglio, S https://iris.unito.it/handle/2318/1617782

Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia.
2014-01-01 F. Arruga; B. Gizdic; S. Serra; T. Vaisitti; C. Ciardullo; M. Coscia; L. Laurenti; G. D'Arena; O. Jaksic; G. Inghirami; D. Rossi; G. Gaidano; S. Deaglio https://iris.unito.it/handle/2318/147404

Abstract 2302: The extracellular form of NAMPT contributes to creating a proinflammatory environment in chronic lymphocytic leukemia
2013-01-01 Audrito, Valentina; Serra, Sara; Vaisitti, Tiziana; Raffaelli, Nadia; Laurenti, Luca; D'Arena, Giovanni; Rossi, Davide; Gaidano, Gianluca; Rizzi, Menico; Deaglio, Silvia https://iris.unito.it/handle/2318/1717781

Regulation Of CLL Growth and Trafficking By The Enzymatic Functions Of CD38: Implications For Therapeutic Targeting
2013-01-01 Vaisitti T, Audrito V, Serra S, Social G, Zucchetto A, Tissino E, Pagnani A, Vitale C, Coscia M, Gattei V, Bruzzone S, Deaglio S https://iris.unito.it/handle/2318/1695878

CD38 signals up-regulate expression and functions of matrix metalloproteinase-9 in chronic lymphocytic leukemia cells.
2013-01-01 Vaisitti T; Serra S; Pepper C; Rossi D; Laurenti L; Gaidano G; Malavasi F; Deaglio S. https://iris.unito.it/handle/2318/118633

Multiple metamorphoses of CD38 from prognostic marker to disease modifier to therapeutic target in chronic lymphocytic leukemia.
2013-01-01 Vaisitti T; Audrito V; Serra S; Bologna C; Arruga F; Brusa D; Buonincontri R; Gizdic B; Deaglio S. https://iris.unito.it/handle/2318/142837

Targeting the microenvironment in chronic lymphocytic leukemia offers novel therapeutic options.
2013-01-01 Audrito V; Vaisitti T; Serra S; Bologna C; Brusa D; Malavasi F; Deaglio S. https://iris.unito.it/handle/2318/118692

SLAMF1/CD150 IS A SIGNALING RECEPTOR EXPRESSED BY A SUBSET OF CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS CHARACTERIZED BY A FAVORABLE PROGNOSIS
2012-01-01 Bologna C; Buonincontri R; Serra S; Vaisitti T; Audrito V; Brusa D; Rossi D; Coscia M; Gaidano G; Terhorst C; Deaglio S https://iris.unito.it/handle/2318/130983

Slamf-1/CD150 Is a Signaling Receptor Expressed by a Subset of Chronic Lymphocytic Leukemia Patients Characterized by a Favorable Prognosis
2012-01-01 Cinzia Bologna; Roberta Buonincontri; Sara Serra; Tiziana Vaisitti; Valentina Audrito; Davide Brusa; Davide Rossi; Marta Coscia; Gianluca Gaidano; Cox Terhorst; Silvia Deaglio https://iris.unito.it/handle/2318/133673

Abstract 5170: Metabolism and cancer: The CD38-NAMPT connection in chronic lymphocytic leukemia
2012-01-01 Audrito, Valentina; Vaisitti, Tiziana; Serra, Sara; Rossi, Davide; D'Arena, Giovanni; Laurenti, Luca; Gaidano, Gianluca; Malavasi, Fabio; Deaglio, Silvia https://iris.unito.it/handle/2318/1717782

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
2012-01-01 Rossi D; Trifonov V; Fangazio M; Bruscaggin A; Rasi S; Spina V; Monti S; Vaisitti T; Arruga F; Famà R; Ciardullo C; Greco M; Cresta S; Piranda D; Holmes A; Fabbri G; Messina M; Rinaldi A; Wang J; Agostinelli C; Piccaluga PP; Lucioni M; Tabbò F; Serra R; Franceschetti S; Deambrogi C; Daniele G; Gattei V; Marasca R; Facchetti F; Arcaini L; Inghirami G; Bertoni F; Pileri SA; Deaglio S; Foà R; Dalla-Favera R; Pasqualucci L; Rabadan R; Gaidano G. https://iris.unito.it/handle/2318/118632

The CD49d/CD29 complex is physically and functionally associated with CD38 in B-cell chronic lymphocytic leukemia cells.
2012-01-01 Zucchetto A; Vaisitti T; Benedetti D; Tissino E; Bertagnolo V; Rossi D; Bomben R; Dal Bo M; Del Principe MI; Gorgone A; Pozzato G; Gaidano G; Del Poeta G; Malavasi F; Deaglio S; Gattei V. https://iris.unito.it/handle/2318/113087

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild type chronic lymphocytic leukemia.
2012-01-01 Rossi D; Fangazio M; Rasi S; Vaisitti T; Monti S; Cresta S; Chiaretti S; Del Giudice I; Fabbri G; Bruscaggin A; Spina V; Deambrogi C; Marinelli M; Famà R; Greco M; Daniele G; Forconi F; Gattei V; Bertoni F; Deaglio S; Pasqualucci L; Guarini A; Dalla-Favera R; Foà R; Gaidano G. https://iris.unito.it/handle/2318/97894

Alteration of BIRC3 and multiple other NF-kappaB pathway genes in splenic marginal zone lymphoma.
2011-01-01 Rossi D; Deaglio S; Dominguez-Sola D; Rasi S; Vaisitti T; Agostinelli C; Spina V; Bruscaggin A; Monti S; Cerri M; Cresta S; Fangazio M; Arcaini L; Lucioni M; Marasca R; Thieblemont C; Capello D; Facchetti F; Kwee I; Pileri SA; Foà R; Bertoni F; Dalla-Favera R; Pasqualucci L; Gaidano G https://iris.unito.it/handle/2318/91359

Abstract 2630: Nicotinamide activates the p53/miR-34a/SIRT1 tumor suppressor network leading to apoptosis of chronic lymphocytic leukemia cells
2011-01-01 Audrito, Valentina; Vaisitti, Tiziana; Rossi, Davide; Gottardi, Daniela; D'Arena, Giovanni; Laurenti, Luca; Gaidano, Gianluca; Malavasi, Fabio; Deaglio, Silvia https://iris.unito.it/handle/2318/1717784

E2A is a transcriptional regulator of CD38 expression in chroniclymphocytic leukemia
2011-01-01 Saborit-Villarroya I; Vaisitti T; Rossi D; D'Arena G; Gaidano G; Malavasi F; Deaglio S https://iris.unito.it/handle/2318/80513

CD73-Generated Extracellular Adenosine Creates Microenvironmental Conditions Favoring Growth and Survival of Chronic Lymphocytic Leukemia Cells
2011-01-01 Sara Serra; Alberto Horenstein; Tiziana Vaisitti; Davide Brusa; Davide Rossi; Luca Laurenti; Giovanni D'Arena; Marta Coscia; Claudio Tripodo; Giorgio Inghirami; Simon Robson; Gianluca Gaidano; Fabio Malavasi; Silvia Deaglio https://iris.unito.it/handle/2318/121055

CD38 in chronic lymphocytic leukemia: from bench to bedside?
2011-01-01 Deaglio S; Vaisitti T; Serra S; Audrito V; Bologna C; D'Arena G; Laurenti L; Gottardi D; Malavasi F https://iris.unito.it/handle/2318/88826

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death
2011-01-01 Serra S; Horenstein AL; Vaisitti T; Brusa D; Rossi D; Laurenti L; D'Arena G; Coscia M; Tripodo C; Inghirami G; Robson SC; Gaidano G; Malavasi F; Deaglio S. https://iris.unito.it/handle/2318/92523

A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome
2011-01-01 Rasi S; Spina V; Bruscaggin A; Vaisitti T; Tripodo C; Forconi F; De Paoli L; Fangazio M; Sozzi E; Cencini E; Laurenti L; Marasca R; Visco C; Xu-Monette ZY; Gattei V; Young KH; Malavasi F; Deaglio S; Gaidano G; Rossi D https://iris.unito.it/handle/2318/80240

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.
2011-01-01 Rossi D; Bruscaggin A; Spina V; Rasi S; Khiabanian H; Messina M; Fangazio M; Vaisitti T; Monti S; Chiaretti S; Guarini A; Del Giudice I; Cerri M; Cresta S; Deambrogi C; Gargiulo E; Gattei V; Forconi F; Bertoni F; Deaglio S; Rabadan R; Pasqualucci L; Foà R; Dalla-Favera R; Gaidano G. https://iris.unito.it/handle/2318/91686

Nicotinamide Blocks Proliferation and Induces Apoptosis of Chronic Lymphocytic Leukemia Cells through Activation of the p53/miR-34a/SIRT1 Tumor Suppressor Network.
2011-01-01 Audrito V; Vaisitti T; Rossi D; Gottardi D; D'Arena G; Laurenti L; Gaidano G; Malavasi F; Deaglio S https://iris.unito.it/handle/2318/92020

NAD+-metabolizing ecto-enzymes shape tumor-host interactions: the chronic lymphocytic leukemia model.
2011-01-01 Vaisitti T; Audrito V; Serra S; Bologna C; Brusa D; Malavasi F; Deaglio S https://iris.unito.it/handle/2318/91302

CD38/CD31 interactions activate genetic pathways leading toproliferation and migration in chronic lymphocytic leukemia cells
2010-01-01 Deaglio S; Aydin S; Grand MM; Vaisitti T; Bergui L; D'Arena G; Chiorino G; Malavasi F https://iris.unito.it/handle/2318/72919

CD38 as a molecular compass guiding topographical decisions of chronic lymphocytic leukemia cells
2010-01-01 Deaglio S; Vaisitti T; Zucchetto A; Gattei V; Malavasi F https://iris.unito.it/handle/2318/75312

CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells
2010-01-01 Vaisitti T; Aydin S; Rossi D; Cottino F; Bergui L; D'Arena G; Bonello L; https://iris.unito.it/handle/2318/75745

Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology
2008-01-01 F. MALAVASI; S. DEAGLIO; A. FUNARO; E. FERRERO; A.L. HORENSTEIN ; E. ORTOLAN; T. VAISITTI; S. AYDIN https://iris.unito.it/handle/2318/35642

CD38 at the junction between prognostic marker and therapeutic target
2008-01-01 Deaglio S; Aydin S; Vaisitti T; Bergui L; Malavasi F https://iris.unito.it/handle/2318/58959

CD38/CD19: a lipid raft dependent signaling complex in human B cells
2007-01-01 DEAGLIO S; VAISITTI T; BILLINGTON R; BERGUI L; OMEDE' P; GENAZZANI AA; MALAVASI F https://iris.unito.it/handle/2318/35885

CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential
2007-01-01 DEAGLIO S; VAISITTI T; AYDIN S; BERGUI L; D'ARENA G; BONELLO L; OMEDÉ P; SCATOLINI M; JAKSIC O; CHIORINO G; EFREMOV D; MALAVASI F https://iris.unito.it/handle/2318/34133

Prognostic significance of combined analysis of ZAP-70 and CD38 in chronic lymphocytic leukemia
2007-01-01 D'ARENA G; TARNANI M; RUMI C; VAISITTI T; AYDIN S; DE FILIPPI R; PERRONE F; PINTO A; CHIUSOLO P; DEAGLIO S; MALAVASI F; LAURENTI L https://iris.unito.it/handle/2318/40854

In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia
2006-01-01 DEAGLIO S; VAISITTI T; AYDIN S; FERRERO E; MALAVASI F https://iris.unito.it/handle/2318/38901

CD38 and CD157 as receptors of the immune system: a bridge between innate and adaptive immunity
2006-01-01 MALAVASI F; DEAGLIO S; FERRERO E; FUNARO A; SANCHO J; AUSIELLO CM; ORTOLAN E; VAISITTI T; ZUBIAUR M; FEDELE G; AYDIN S; TIBALDI EV; DURELLI I; LUSSO R; CORNO F; HORENSTEIN AL https://iris.unito.it/handle/2318/36336

CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells
2006-01-01 FRASCA L; FEDELE G; DEAGLIO S; CAPUANO C; PALAZZO R; VAISITTI T; MALAVASI F; AUSIELLO CM https://iris.unito.it/handle/2318/35536

Cationization of monoclonal antibodies: another step towards the 'magic bullet'?
2005-01-01 T. VAISITTI; S. DEAGLIO; F. MALAVASI https://iris.unito.it/handle/2318/41280

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival
2005-01-01 DEAGLIO S; VAISITTI T; BERGUI L; BONELLO L; HORENSTEIN AL; TAMAGNONE L; BOUMSELL L; MALAVASI F https://iris.unito.it/handle/2318/42620

Courses

• ADE Applicazioni di next generation sequencing per la diagnosi di malattie genetiche suscettibili di trapianto (SME0950)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Basi biologiche, molecolari e di genetica umana (canale D) (SME0881)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Genetica Medica - D.M. 270/04 - (Canale B) (SSP0381C)
  Corso di Laurea in Infermieristica - A.O.U. Città della Salute e della Scienza di Torino
• Genetica Umana (D.M. 270/04) (SSP0520C)
  Corso di Laurea in Tecniche di Laboratorio Biomedico - Torino
• Genetica medica (SSPO381)
  Corso di laurea in Infermieristica - Aosta
• Genetica umana (canale D) (SME0881C)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• I. BIOLOGIA E GENETICA (D.M. 270/04) (SSP0520)
  Corso di Laurea in Tecniche di Laboratorio Biomedico - Torino
• STORIA ETICA E DEONTOLOGIA PROFESSIONALE (SSPO381)
  Corso di laurea in Infermieristica - Aosta
• Storia, etica e deontologia professionale (Canale B) - D.M. 270/04 - (SSP0381)
  Corso di Laurea in Infermieristica - A.O.U. Città della Salute e della Scienza di Torino
• TIROCINIO di GENETICA, BIOLOGIA E ASPETTI TRASLAZIONALI DEI TUMORI (SME1076)
  Corso di Laurea Magistrale in Biotecnologie Mediche - Classe LM-9

Research topics

Gruppi di ricerca

Genetica e Immunologia dei Trapianti

Genomica funzionale

 

Research projects

• Probing Richter's syndrome by multiple "omics" approaches to find its Achille's heel
• Analisi della risposta terapeutica di cellule neoplastiche di sindrome di Richter: colpire nuovi bersagli molecolari

Academic bodies

• Consiglio

Office hours

Ricevimento studenti su appuntamento, inviando una mail a: tiziana.vaisitti@unito.it